Cognitive Systems Lab, Hewlett-Packard Laboratories, 1501 Page Mill Road, Palo Alto, California 94304, United States.
Anal Chem. 2012 Nov 6;84(21):9303-9. doi: 10.1021/ac302025q. Epub 2012 Oct 15.
Simple and rapid detection of trace amounts of melamine in milk products has been achieved with a portable sensor system based on surface-enhanced Raman scattering (SERS). The sensor system comprised high-performance gold nanofinger SERS sensor chips and a custom-built prototype portable Raman spectrometer. Compared to the FDA procedure and previously reported studies that were limited to laboratory settings, our sampling and analytical methods are simple (with one sampling step), less time-consuming, and cost-effective. We found the limit of detection (LOD) of the melamine is 120 parts per trillion (ppt) in water and 100 parts per billion (ppb) in infant formula, which are well below the FDA's tolerance level of 1 ppm in infant formula.
基于表面增强拉曼散射（SERS）的便携式传感器系统可实现对奶制品中痕量三聚氰胺的简单、快速检测。该传感器系统由高性能金纳米指 SERS 传感器芯片和定制的便携式拉曼光谱仪组成。与美国食品和药物管理局（FDA）的程序以及以前仅限于实验室环境的研究相比，我们的采样和分析方法简单（只需进行一次采样步骤），耗时更少，并且具有成本效益。我们发现，水基质中的三聚氰胺检出限（LOD）为 120ppt，婴儿配方中的检出限为 100ppb，远低于 FDA 规定的婴儿配方中 1ppm 的耐受水平。
