Yadav Akanksha, Yadav Anil K, Tarannum Nazia, Kumar Dev
Department of Physics, Chaudhary Charan Singh University, Meerut 250004 India.
Department of Chemistry, Chaudhary Charan Singh University, Meerut 250004 India.
ACS Omega. 2024 Jan 5;9(2):2687-2695. doi: 10.1021/acsomega.3c07663. eCollection 2024 Jan 16.
Melamine is a chemical compound that is added to dairy products to increase the apparent protein content for higher profit margins. However, extended consumption of melamine can cause health risks. The SERS technique has proven to be an important tool for detecting small compounds, such as melamine. Here, a paper-based flexible nanoparticles (NPs)-hybrid SERS substrate was designed by drop-casting pegylated gold nanoparticles (AuNPs) on the filter papers. In SERS characterization, this substrate exhibited an enhancement factor of 10 and a limit of detection (LOD) as low as 10 M for Rhodamine 6G dye. Furthermore, we successfully utilized these substrates to detect the melamine spiked milk sample with an LOD as low as 0.01 ppm. This hybrid SERS substrate offers a low-cost, biocompatible, and easy-to-use fabrication for large-scale production, which may be widely used in food safety applications.
三聚氰胺是一种添加到乳制品中以提高表观蛋白质含量从而获取更高利润率的化合物。然而，长期食用三聚氰胺会带来健康风险。表面增强拉曼光谱（SERS）技术已被证明是检测三聚氰胺等小分子化合物的重要工具。在此，通过将聚乙二醇化金纳米粒子（AuNPs）滴铸在滤纸上，设计了一种基于纸张的柔性纳米粒子（NPs）混合SERS基底。在SERS表征中，该基底对罗丹明6G染料的增强因子为10，检测限（LOD）低至10 M。此外，我们成功地利用这些基底检测了加标三聚氰胺的牛奶样品，其LOD低至0.01 ppm。这种混合SERS基底提供了一种低成本、生物相容性好且易于使用的制造方法，可用于大规模生产，有望在食品安全应用中得到广泛应用。
