Center for Research in Biological Systems, University of California San Diego, La Jolla, CA 92093, USA.
Bioinformatics. 2013 Jan 1;29(1):122-3. doi: 10.1093/bioinformatics/bts567. Epub 2012 Oct 8.
Numerous metagenomics projects have produced tremendous amounts of sequencing data. Aligning these sequences to reference genomes is an essential analysis in metagenomics studies. Large-scale alignment data call for intuitive and efficient visualization tool. However, current tools such as various genome browsers are highly specialized to handle intraspecies mapping results. They are not suitable for alignment data in metagenomics, which are often interspecies alignments. We have developed a web browser-based desktop application for interactively visualizing alignment data of metagenomic sequences. This viewer is easy to use on all computer systems with modern web browsers and requires no software installation.
大量的宏基因组学项目已经产生了大量的测序数据。将这些序列与参考基因组进行比对是宏基因组学研究中的一个重要分析步骤。大规模的比对数据需要直观、高效的可视化工具。然而,目前的工具,如各种基因组浏览器,都是专门用于处理种内映射结果的。它们不适合处理宏基因组学中的比对数据,这些数据通常是种间比对。我们开发了一个基于网络浏览器的桌面应用程序,用于交互式地可视化宏基因组序列的比对数据。这个查看器易于在所有具有现代网络浏览器的计算机系统上使用,并且不需要软件安装。