Kollmann E, Seyberth H W, Sulyok E
Baranya Megyei Tanács Gyermekkórháza, Pécs.
Orv Hetil. 1990 Feb 11;131(6):303-6.
The authors describe the history of a nine year old girl, with a disease that seemed to be hyperprostaglandin-E syndrome. They give a survey of the literature about the pathophysiological cause of the disease, the clinical and laboratory findings and the effect of indomethacin, which can inhibit the synthesis of prostaglandins. Prolonged treatment with indomethacin can decrease the urinary excretion of prostaglandine, polyuria and hypercalciuria and it can moderate the growth retardation. They found the same but milder clinical and laboratory features at the four year old brother of the patient too.
作者描述了一名9岁女孩的病史，其患有一种似乎是高前列腺素E综合征的疾病。他们对有关该疾病病理生理原因、临床和实验室检查结果以及吲哚美辛（可抑制前列腺素合成）作用的文献进行了综述。长期使用吲哚美辛治疗可减少前列腺素的尿排泄、多尿和高钙尿，并可缓解生长发育迟缓。他们在该患者4岁的弟弟身上也发现了相同但较轻的临床和实验室特征。
