Schwarz M L R, Schneider-Wald B, Krase A, Richter W, Reisig G, Kreinest M, Heute S, Pott P P, Brade J, Schütte A
Sektion experimentelle Orthopädie und Unfallchirurgie, Orthopädisch-Unfallchirurgisches Zentrum, Universitätsmedizin Mannheim, Medizinische Fakultät Mannheim, Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.
Orthopade. 2012 Oct;41(10):827-36. doi: 10.1007/s00132-012-1951-6.
Values for the friction coefficient of articular cartilage are given in ranges of percentage and lower and are calculated as a quotient of the friction force and the perpendicular loading force acting on it. Thus, a sophisticated system has to be provided for analysing the friction coefficient under different conditions in particular when cartilage should be coupled as friction partner. It is possible to deep-freeze articular cartilage before measuring the friction coefficient as the procedure has no influence on the results. The presented tribological system was able to distinguish between altered and native cartilage. Furthermore, tissue engineered constructs for cartilage repair were differentiated from native cartilage probes by their friction coefficient. In conclusion a tribological equipment is presented to analyze the friction coefficient of articular cartilage, in vivo generated cartilage regenerates and in vitro tissue engineered constructs regarding their biomechanical properties for quality assessment.
关节软骨摩擦系数的值以百分比范围及更低的形式给出,并通过摩擦力与作用于其上的垂直加载力的商来计算。因此,必须提供一个复杂的系统来分析不同条件下的摩擦系数,特别是当软骨作为摩擦伙伴耦合时。在测量摩擦系数之前对关节软骨进行深度冷冻是可行的,因为该过程对结果没有影响。所展示的摩擦学系统能够区分改变的软骨和天然软骨。此外,用于软骨修复的组织工程构建体通过其摩擦系数与天然软骨探针区分开来。总之,展示了一种摩擦学设备,用于分析关节软骨、体内生成的软骨再生组织和体外组织工程构建体的摩擦系数,以评估它们的生物力学性能。