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自动性房性心动过速的外科治疗

Surgical treatment of automatic atrial tachycardias.

作者信息

Hendry P J, Packer D L, Anstadt M P, Plunkett M D, Lowe J E

机构信息

Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710.

出版信息

Ann Thorac Surg. 1990 Feb;49(2):253-9; discussion 259-60. doi: 10.1016/0003-4975(90)90147-x.

Abstract

From 1979 to 1989, 18 patients were seen in the Electrophysiology Service, Duke University Medical Center, with automatic atrial tachycardia. There were 8 male and 10 female patients with a mean age of 28.1 +/- 2.9 years. Electrophysiological mapping localized automatic foci to right atrial sites (14 patients) and left atrial sites (4 patients). Depending on origin of the focus, patients were further diagnosed as having either chronic ectopic atrial tachycardia or inappropriate sinus tachycardia. Of the 15 patients with chronic ectopic atrial tachycardia, 6 responded to medical treatment; in 9, the tachycardia was not adequately controlled. Six of them were referred for surgical intervention. All 3 patients with inappropriate sinus tachycardia underwent operative therapy. In the surgical group of patients with chronic ectopic atrial tachycardia, all 6 had a tachycardia-induced cardiomyopathy with ejection fractions ranging from 14% to 27% (mean ejection fraction, 21% +/- 2.7%). Surgical techniques used (alone or in combination) included an isolation procedure in 1 patient, cryoablation in 4 patients, and excision of atrial appendages or portions of atrial free walls in 7. Normal sinus rhythm developed in all surgical patients except 1 patient who had intractable congestive heart failure preoperatively and died of this condition and stroke. The overall success rates for medical and surgical therapy were 33.3% and 88.9%, respectively (p less than 0.01). Long-term follow-up was possible for 7 (87.5%) of 8 patients 3 to 7 years after operation. All patients with chronic ectopic atrial tachycardia were cured, but only 1 of 3 patients with inappropriate sinus tachycardia was in sinus rhythm.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1979年至1989年期间,杜克大学医学中心电生理科诊治了18例自动性房性心动过速患者。其中男性8例,女性10例,平均年龄28.1±2.9岁。电生理标测将自动节律点定位于右心房部位(14例患者)和左心房部位(4例患者)。根据节律点的起源,患者进一步被诊断为慢性异位房性心动过速或不适当窦性心动过速。15例慢性异位房性心动过速患者中,6例对药物治疗有反应;9例患者心动过速未得到充分控制。其中6例患者被转诊接受手术干预。3例不适当窦性心动过速患者均接受了手术治疗。在慢性异位房性心动过速手术组患者中,所有6例均有心动过速性心肌病,射血分数在14%至27%之间(平均射血分数为21%±2.7%)。所采用的手术技术(单独或联合使用)包括1例患者采用隔离手术,4例患者采用冷冻消融术,7例患者切除心房附件或心房游离壁部分。除1例术前患有难治性充血性心力衰竭并死于该病和中风的患者外,所有手术患者均恢复了正常窦性心律。药物治疗和手术治疗的总体成功率分别为33.3%和88.9%(P<0.01)。8例患者中有7例(87.5%)在术后3至7年进行了长期随访。所有慢性异位房性心动过速患者均治愈,但3例不适当窦性心动过速患者中只有1例恢复窦性心律。(摘要截短于250字)

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