Department of Ophthalmology, Yeouido St. Mary's Hospital, #62 Yeouido-dong, Yeoungdeungpo-gu, Seoul 150-713, Korea.
Jpn J Ophthalmol. 2013 Jan;57(1):47-56. doi: 10.1007/s10384-012-0188-6. Epub 2012 Oct 12.
To investigate the common side effects of topical antiglaucoma medication, factors affecting compliance, and the utilization of herbal medicine for glaucoma treatment in South Korea.
A cross-sectional multicenter hospital-based study. In-depth interviews using a structured questionnaire were conducted with 581 individuals diagnosed with glaucoma. Additional eligibility requirements were: all participants were diagnosed with glaucoma in one or both eyes and prescribed eye drops at least one month before the start of the study, and were in a suitable condition for an interview. The frequency of response for each category in the interview questionnaire was analyzed.
Conjunctival injection, a stinging sensation, and blurred vision were the most frequently reported side effects, among which blurred vision was the most unbearable. Patient knowledge of glaucoma was the only factor associated with the patient's self-evaluation of compliance. Forgetfulness was the most common reason for nonadherence. Only 2.9 % of patients were taking herbal medicine.
Physicians should address a patient's complaint of blurred vision resulting from medication. Complete initial explanation of the consequences of nonadherence and of the potential vision loss from glaucoma are critical elements in improving patient adherence in Asian populations.
调查韩国局部抗青光眼药物的常见副作用、影响依从性的因素以及用于青光眼治疗的草药利用情况。
一项基于医院的横断面多中心研究。对 581 名确诊青光眼的患者进行了深入的访谈，使用结构化问卷。额外的入选标准为：所有患者在研究开始前至少一个月在一只或两只眼睛被诊断为青光眼，并适合接受访谈。对访谈问卷中每个类别的响应频率进行了分析。
结膜充血、刺痛感和视力模糊是最常报告的副作用，其中视力模糊是最难以忍受的。患者对青光眼的了解是唯一与患者自我评估依从性相关的因素。健忘是不依从的最常见原因。仅有 2.9%的患者在服用草药。
医生应处理患者因药物引起的视力模糊的抱怨。完整地解释不依从的后果以及青光眼可能导致的视力丧失是提高亚洲人群患者依从性的关键因素。
