Kocisková D, Borecký L, Oravec C
Acta Biol Med Ger. 1979;38(5-6):837-41.
Relatively high levels of interferon were achieved in rat sera by intracardial inoculation with Sindbis virus followed 15 min later by intraperitoneal application of dimethylsulfoxide. At intervals when interferon titres reached the maximum, the levels of complement were decreased as compared with the control group of rats. Single administration of dimethylsulfoxide did neither induce interferon nor influence the complement levels in sera of rats of the Dobrá Voda breed tested. Similar results were obtained with concentrated Newcastle disease virus inoculated intraperitoneally. Of interest is the finding that properdin levels seem to increase at the same time as interferon.
通过心内接种辛德毕斯病毒，随后在15分钟后腹腔注射二甲基亚砜，可使大鼠血清中干扰素达到相对较高水平。在干扰素滴度达到最大值的各个时间点，与对照组大鼠相比，补体水平降低。单独给予二甲基亚砜既不诱导干扰素产生，也不影响所测试的多布拉沃达品种大鼠血清中的补体水平。腹腔注射浓缩新城疫病毒也得到了类似结果。有趣的是，发现备解素水平似乎与干扰素同时升高。
