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再生医学研究——现状与展望

Researches on regenerative medicine-current state and prospect.

作者信息

Wang Zheng-Guo, Xiao Kai

机构信息

Research Institute of Surgery, Daping, Chongqing 400042, China.

出版信息

Chin J Traumatol. 2012;15(5):259-67.

PMID:23069095
Abstract

Since 1980s, the rapid development of tissue engineering and stem cell research has pushed regenerative medicine to a new fastigium, and regenerative medicine has become a noticeable research field in the international biology and medicine. In China, about 100 million patients need repair and regeneration treatment every year, while the number is much larger in the world. Regenerative medicine could provide effective salvation for these patients. Both Chinese Academy of Sciences and Chinese Academy of Engineering have made roadmaps of 2010-2050 and 2011-2030 for regenerative medicine. The final goal of the two roadmaps is to make China go up to leading position in most research aspects of regenerative medicine. In accord with this strategy, the government and some enterprises have invested 3-5 billion RMB (0.5-0.8 billion USD) for the research on regenerative medicine. In order to push the translation of regenerative medicine forward-from bench to bedside, a strategic alliance has been established, and it includes 27 top-level research institutes, medical institutes, colleges, universities and enterprises in the field of stem cell and regeneration medicine. Recently the journal, Science, has published a special issue-Regenerative Medicine in China, consisting of 35 papers dealing with stem cell and regeneration, tissue engineering and regeneration, trauma and regeneration and bases for tissue repair and regenerative medicine. It is predicated that a greater breakthrough in theory and practice of regenerative medicine will be achieved in the near future (20 to 30 years).

摘要

自20世纪80年代以来,组织工程学和干细胞研究的快速发展将再生医学推向了一个新的高峰,再生医学已成为国际生物学和医学领域一个引人注目的研究领域。在中国,每年约有1亿患者需要修复和再生治疗,而在全球范围内这一数字要大得多。再生医学可以为这些患者提供有效的救助。中国科学院和中国工程院都制定了2010 - 2050年以及2011 - 2030年的再生医学路线图。这两个路线图的最终目标是使中国在再生医学的大多数研究方面位居领先地位。按照这一战略,政府和一些企业已投入30 - 50亿元人民币(5 - 8亿美元)用于再生医学研究。为了推动再生医学从实验室到临床应用的转化,已成立了一个战略联盟,它包括干细胞与再生医学领域的27家顶级研究机构、医学机构、高校和企业。最近,《科学》杂志出版了一期中国再生医学专刊,其中包含35篇关于干细胞与再生、组织工程与再生、创伤与再生以及组织修复和再生医学基础的论文。据预测,再生医学在理论和实践方面将在不久的将来(20至30年)取得更大突破。

相似文献

1
Researches on regenerative medicine-current state and prospect.再生医学研究——现状与展望
Chin J Traumatol. 2012;15(5):259-67.
2
[Research development of amniotic fluid-derived stem cells in regenerative medicine].[羊水来源干细胞在再生医学中的研究进展]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 Oct;27(10):1262-6.
3
China's landscape in regenerative medicine.中国的再生医学领域。
Biomaterials. 2017 Apr;124:78-94. doi: 10.1016/j.biomaterials.2017.01.044. Epub 2017 Feb 3.
4
Tissue engineering of skin and soft tissue augmentation, medical view.皮肤组织工程与软组织增强,医学视角。
J Med Assoc Thai. 2010 Dec;93 Suppl 7:S332-6.
5
[Tissue regeneration is a key tool for burn tissue repair].组织再生是烧伤组织修复的关键手段。
Zhonghua Shao Shang Za Zhi. 2011 Feb;27(1):6-7.
6
[Important contribution and necessity of stem cells scaffolds for regenerative medicine and the therapeutic applications].[干细胞支架在再生医学中的重要贡献、必要性及治疗应用]
Nihon Rinsho. 2008 May;66(5):881-6.
7
What is regenerative medicine? Emergence of applied stem cell and developmental biology.什么是再生医学?应用干细胞与发育生物学的兴起。
Expert Opin Biol Ther. 2004 Jun;4(6):773-81. doi: 10.1517/14712598.4.6.773.
8
Regeneration-on-a-chip? The perspectives on use of microfluidics in regenerative medicine.芯片上的再生?微流控在再生医学中的应用展望。
Lab Chip. 2013 Sep 21;13(18):3512-28. doi: 10.1039/c3lc50293g.
9
Progress and potential for regenerative medicine.再生医学的进展与潜力
Annu Rev Med. 2007;58:299-312. doi: 10.1146/annurev.med.58.082405.095329.
10
Tissue engineering and regenerative medicine in basic research: a year in review of 2014.基础研究中的组织工程与再生医学:2014年年度回顾
Tissue Eng Part B Rev. 2015 Apr;21(2):167-76. doi: 10.1089/ten.TEB.2014.0626. Epub 2015 Mar 12.

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An Investigation about Gene Modules Associated with hDPSC Differentiation for Adolescents.青少年人牙髓干细胞分化相关基因模块的研究
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