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基础研究中的组织工程与再生医学:2014年年度回顾

Tissue engineering and regenerative medicine in basic research: a year in review of 2014.

作者信息

Huang Jia, Lin Xunxun, Shi Yuan, Liu Wei

机构信息

Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai Key Laboratory of Tissue Engineering Research, National Tissue Engineering Center of China, Shanghai, China .

出版信息

Tissue Eng Part B Rev. 2015 Apr;21(2):167-76. doi: 10.1089/ten.TEB.2014.0626. Epub 2015 Mar 12.

Abstract

Tissue engineering and regenerative medicine (TERM) remains to be one of the fastest growing fields, which covers a wide scope of topics of both basic and applied biological researches. This overview article summarized the advancements in basic researches of TERM area, including stem cell biology, cell engineering, somatic nuclear transfer, genomic editing, discovery of new tissue progenitor/stem cells, and immunomodulation of stem cells and tissue regeneration. It reflects the cutting-edge achievements in basic researches, which will lay solid scientific foundation for future TERM translational researches.

摘要

组织工程与再生医学(TERM)仍然是发展最快的领域之一,涵盖了基础生物学研究和应用生物学研究的广泛主题。这篇综述文章总结了TERM领域基础研究的进展,包括干细胞生物学、细胞工程、体细胞核移植、基因组编辑、新组织祖细胞/干细胞的发现以及干细胞的免疫调节和组织再生。它反映了基础研究的前沿成果,将为未来的TERM转化研究奠定坚实的科学基础。

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