Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Medical School, 3120 Taubman Center; 1500 E. Medical Center Dr., SPC 5378, Ann Arbor, MI, 48109-5378, USA,
Curr Infect Dis Rep. 2012 Dec;14(6):676-82. doi: 10.1007/s11908-012-0300-6.
Over the past decade, the solid organ transplant community has focused increased attention on unexpected transmission of infectious pathogens from organ donor to recipient. While unexpected donor-derived infections are relatively uncommon, recent cases of transmission of human immunodeficiency virus (HIV) and hepatitis C to multiple recipients, as well as transmission of HIV from a living donor, have further increased interest in improving the safety of solid organ transplantation. This article will review the epidemiology and outcomes associated with unexpected donor-derived infection. Furthermore, the reporting and patient safety process will be discussed, as will preventative measures that can reduce the burden of donor-derived infection.
在过去的十年中，实体器官移植界越来越关注器官供体向受者传播意外传染性病原体的问题。虽然意料之外的供体来源感染相对少见，但最近发生的多例艾滋病毒（HIV）和丙型肝炎病毒从供体向受者传播的病例，以及一例来自活体供者的 HIV 传播病例，进一步增加了人们对提高实体器官移植安全性的兴趣。本文将回顾与意外供体来源感染相关的流行病学和结局。此外，还将讨论报告和患者安全流程，以及可以减轻供体来源感染负担的预防措施。
