Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Indian J Dermatol Venereol Leprol. 2012 Nov-Dec;78(6):715-21. doi: 10.4103/0378-6323.102362.
Segmental vitiligo is a small but unique subset of vitiligo requiring due importance due to its lack of response to medical treatment but excellent response to surgical treatment. Characterization of the pattern of segmental vitiligo will also help to understand the pathogenesis of the disease.
To characterize clinically the features of segmental vitiligo, a cross-sectional clinical study at dermatology outpatient department at AIIMS was carried out.
Consecutive 188 patients were evaluated to characterize the clinical features of segmental vitiligo by detailed history, clinical examination, and photography. Frequency of each clinical feature was calculated.
Certain features such as early onset, initial progression of disease followed by stability, blaschkoid pattern, irregular margins, leucotrichia within and beyond the vitiligo lesion, and islands of pigmented macules within the vitiligo lesion were found to be characteristic of the disease.
A combination of various features such as early onset of disease, blaschkoid pattern, irregular margins, leucotrichia, and islands of pigmented macules within the vitiligo lesion are helpful in diagnosis of the disease.
节段性白癜风是白癜风的一个较小但独特的亚类,由于其对药物治疗反应不佳但对手术治疗反应良好,因此需要给予足够的重视。节段性白癜风模式的特征也有助于了解疾病的发病机制。
为了对节段性白癜风的临床特征进行描述,我们在 AIIMS 的皮肤科门诊进行了一项横断面临床研究。
对 188 例连续患者进行评估,通过详细的病史、临床检查和摄影来描述节段性白癜风的临床特征。计算每个临床特征的频率。
发现某些特征,如疾病的早期发病、疾病的初始进展后稳定、Blaschko 线样模式、不规则边缘、白癜风皮损内和皮损外的白发、以及白癜风皮损内的色素斑岛,都是该疾病的特征。
疾病的早期发病、Blaschko 线样模式、不规则边缘、白发和白癜风皮损内的色素斑岛等各种特征的组合有助于该疾病的诊断。