自动化合成模块综述。
Automation synthesis modules review.
作者信息
Boschi S, Lodi F, Malizia C, Cicoria G, Marengo M
机构信息
PET Radiopharmacy, Nuclear Medicine Department, S.Orsola-Malpighi University Hospital, Bologna, Italy.
出版信息
Appl Radiat Isot. 2013 Jun;76:38-45. doi: 10.1016/j.apradiso.2012.09.010. Epub 2012 Sep 26.
The introduction of (68)Ga labelled tracers has changed the diagnostic approach to neuroendocrine tumours and the availability of a reliable, long-lived (68)Ge/(68)Ga generator has been at the bases of the development of (68)Ga radiopharmacy. The huge increase in clinical demand, the impact of regulatory issues and a careful radioprotection of the operators have boosted for extensive automation of the production process. The development of automated systems for (68)Ga radiochemistry, different engineering and software strategies and post-processing of the eluate were discussed along with impact of automation with regulations.
（68）Ga标记示踪剂的引入改变了神经内分泌肿瘤的诊断方法，可靠的长寿命（68）Ge/（68）Ga发生器的可用性是（68）Ga放射性药物发展的基础。临床需求的大幅增加、监管问题的影响以及对操作人员的严格辐射防护推动了生产过程的广泛自动化。讨论了用于（68）Ga放射化学的自动化系统的发展、不同的工程和软件策略以及洗脱液的后处理，以及自动化对法规的影响。
Zotero 插件