温和噬菌体 AcaML1 完整基因组序列来自极端嗜酸菌嗜酸硫杆菌 ATCC 51756。
Complete genome sequence of temperate bacteriophage AcaML1 from the extreme acidophile Acidithiobacillus caldus ATCC 51756.
机构信息
Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
出版信息
J Virol. 2012 Nov;86(22):12452-3. doi: 10.1128/JVI.02261-12.
Abstract
Development of reproducible genetic tools in the industrially important acidithiobacilli is urgently required. Inducible temperate phages which may be modified in vitro, propagated in suitable hosts, and used to transduce relevant genetic information to other strains and/or species are potentially valuable tools in this field of research. In order to address these current limitations, the genome sequence of an inducible temperate Myoviridae-like bacteriophage from the Acidithiobacillus caldus type strain was annotated and analyzed bioinformatically. Here, we announce the genome sequence of AcaML1 and report major findings from its annotation.
摘要
迫切需要在工业上重要的嗜酸硫杆菌中开发可重复的遗传工具。可体外修饰、在合适的宿主中繁殖、并用于将相关遗传信息转导到其他菌株和/或物种的诱导性温和噬菌体是该研究领域中具有潜在价值的工具。为了解决这些当前的局限性，对来自嗜酸硫杆菌模式株的可诱导温和肌尾噬菌体的基因组序列进行了注释和生物信息学分析。在这里，我们宣布了 AcaML1 的基因组序列，并报告了其注释的主要发现。
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