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非霍奇金淋巴瘤和血管免疫母细胞性淋巴结病中抗EBV抗体的比较研究(作者译)

[Comparative study of anti EBV antibodies in non-Hodgkin's lymphomams and angio-immunoblastic lymphadenopathies (author's transl)].

作者信息

Dumont J, Liabeuf A, Henle W, Ferchal F, Feingold N, Kourilsky F M

出版信息

Bull Cancer. 1979;66(4):373-81.

PMID:230873
Abstract

Antibody titers to Epstein-Barr virus (EBV)--related antigens (viral capsid antigen : VCA; early antigen : EA; and EBV associated nuclear antigen : EBNA) were determined in the sera of 86 patients and 150 matched control subjects. The patients belonged to four histological groups : diffuse and nodular non-hodgkin's lymphomas angio-immunoblastic lymphadenopathies and apparented syndroms. The incidence of antibodies to other herpes-viruses (cytomégalovirus, herpes simplex virus, and varicella zoster virus) was compared. There was a significantly higher incidence of anti VCA and anti EA titers in some patients, not associated with an increase in titres of antibodies to other herpes viruses.

摘要

在86例患者和150例匹配的对照受试者的血清中,测定了针对爱泼斯坦-巴尔病毒(EBV)相关抗原(病毒衣壳抗原:VCA;早期抗原:EA;以及EBV相关核抗原:EBNA)的抗体滴度。患者分为四个组织学组:弥漫性和结节性非霍奇金淋巴瘤、血管免疫母细胞性淋巴结病和明显综合征。比较了针对其他疱疹病毒(巨细胞病毒、单纯疱疹病毒和水痘带状疱疹病毒)的抗体发生率。在一些患者中,抗VCA和抗EA滴度的发生率显著更高,且与针对其他疱疹病毒的抗体滴度增加无关。

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