U.O. Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Clin Chem Lab Med. 2013 Jan;51(1):91-7. doi: 10.1515/cclm-2012-0387.
Hemostasis is a delicate, dynamic and intricate system, in which pro- and anti-coagulant forces cooperate for either maintaining blood fluidity under normal conditions, or else will prompt blood clot generation to limit the bleeding when the integrity of blood vessels is jeopardized. Excessive prevalence of anticoagulant forces leads to hemorrhage, whereas excessive activation of procoagulant forces triggers excessive coagulation and thrombosis. The hemostasis laboratory performs a variety of first, second and third line tests, and plays a pivotal role in diagnostic and monitoring of most hemostasis disturbances. Since the leading targets of Clinical Chemistry and Laboratory Medicine include promotion of progress in fundamental and applied research, along with publication of guidelines and recommendations in laboratory diagnostics, this journal is an ideal source of information on current developments in the laboratory technology of hemostasis, and this article is aimed to celebrate some of the most important and popular articles ever published by the journal in the filed of laboratory hemostasis.
止血是一个精细、动态且复杂的系统，其中促凝和抗凝力量相互配合，以维持血管正常情况下的血液流动性，或者在血管完整性受到威胁时促使血液凝结以限制出血。抗凝力量过度活跃会导致出血，而促凝力量过度激活则会引发过度凝血和血栓形成。止血实验室进行各种一线、二线和三线测试，在大多数止血紊乱的诊断和监测中发挥着关键作用。由于临床化学和实验室医学的主要目标包括促进基础和应用研究的进展，以及在实验室诊断中发布指南和建议，因此该期刊是了解止血实验室技术最新发展的理想信息来源，本文旨在庆祝该期刊在实验室止血领域发表的一些最重要和最受欢迎的文章。
