Laboratory of Pediatric Biology and Research, American Memorial Hospital, CHU of Reims, Reims, France.
Clin Chem Lab Med. 2013 Jan;51(1):65-74. doi: 10.1515/cclm-2012-0548.
HbA(1c) was discovered in the late 1960s and its use as marker of glycemic control has gradually increased over the course of the last four decades. Recognized as the gold standard of diabetic survey, this parameter was successfully implemented in clinical practice in the 1970s and 1980s and internationally standardized in the 1990s and 2000s. The use of standardized and well-controlled methods, with well-defined performance criteria, has recently opened new directions for HbA(1c) use in patient care, e.g., for diabetes diagnosis. Many reports devoted to HbA1c have been published in Clinical Chemistry and Laboratory Medicine (CCLM) journal. This review reminds the major steps of HbA(1c) history, with a special emphasis on the contribution of CCLM in this field.
HbA(1c) 于 20 世纪 60 年代末被发现，其作为血糖控制标志物的应用在过去四十年中逐渐增加。作为糖尿病检测的金标准，该参数于 20 世纪 70 年代和 80 年代在临床实践中成功实施，并于 90 年代和 21 世纪初在国际上标准化。近年来，采用标准化和良好控制的方法，并具有明确的性能标准，为 HbA(1c) 在患者护理中的应用开辟了新的方向，例如用于糖尿病诊断。许多关于 HbA1c 的报告已在《临床化学与检验医学》（CCLM）期刊上发表。这篇综述回顾了 HbA(1c) 的主要发展历程，特别强调了 CCLM 在该领域的贡献。
