Department of Urology, Toronto Western Hospital, Toronto, ON, Canada.
Int Neurourol J. 2012 Sep;16(3):126-31. doi: 10.5213/inj.2012.16.3.126. Epub 2012 Sep 30.
Overactive bladder (OAB) is a common condition. In women, studies have shown that the prevalence of OAB is positively related to increasing body mass index (BMI). Our objective was to define a relationship between BMI and OAB through correlation with urodynamic study (UDS).
A prospective study was conducted. Ambulatory women aged 18 years or older who had symptoms of OAB for at least 3 months were enrolled. Patients answered a questionnaire, had their weight and height recorded, and underwent UDS. Patients were categorized into 3 groups as follows: group 1, BMI<25; group 2, BMI 25 to 29.9; and group 3, BMI≥30.
A total of 113 patients were examined (group 1, n=32; group 2, n=40; group 3, n=41). The patients' mean ages were 50, 55, and 59 years for groups 1, 2, and 3, respectively (P<0.05). Group 3 showed a significant increase in the incidence of subjective mixed leakage and the number of pads used compared with groups 1 and 2. No significant differences were seen among the groups in duration of symptoms, OAB V-8 score, or the incidence of subjective urgency or stress leakage. The UDS parameters of groups 1, 2, and 3 showed no statistically significant differences for most variables. Group 3 showed a significant increase in the incidence of urge leakage by UDS compared with group 2 only.
Increasing BMI was age related. A BMI≥30 showed a higher incidence of subjective urinary mixed leakage and pad use. UDS showed no significant correlation between OAB and any BMI category for most UDS parameters.
膀胱过度活动症(OAB)是一种常见病症。在女性中,研究表明 OAB 的患病率与体重指数(BMI)的增加呈正相关。我们的目的是通过与尿动力学研究(UDS)的相关性来定义 BMI 与 OAB 之间的关系。
进行了一项前瞻性研究。招募了年龄在 18 岁或以上、有 OAB 症状至少 3 个月的门诊女性患者。患者回答问卷,记录体重和身高,并进行 UDS。患者分为 3 组:第 1 组,BMI<25;第 2 组,BMI 25 至 29.9;第 3 组,BMI≥30。
共检查了 113 例患者(第 1 组,n=32;第 2 组,n=40;第 3 组,n=41)。第 1、2、3 组患者的平均年龄分别为 50、55 和 59 岁(P<0.05)。与第 1 组和第 2 组相比,第 3 组患者主观混合性漏尿和使用尿垫的发生率显著增加。3 组间症状持续时间、OAB V-8 评分或主观急迫性和压力性漏尿发生率无显著差异。第 1、2 和 3 组的 UDS 参数在大多数变量方面无统计学差异。仅第 3 组 UDS 显示急迫性漏尿的发生率显著高于第 2 组。
BMI 的增加与年龄有关。BMI≥30 与主观混合性尿漏和使用尿垫的发生率增加有关。UDS 显示 OAB 与大多数 BMI 类别之间没有显著相关性。