大麻戒断综合征的治疗：病例报告。
Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report.
机构信息
Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo and INCT Translational Medicine (CNPq)-São Paulo, Brazil.
出版信息
J Clin Pharm Ther. 2013 Apr;38(2):162-4. doi: 10.1111/jcpt.12018. Epub 2012 Oct 24.
WHAT IS KNOWN AND OBJECTIVE
Cannabis withdrawal in heavy users is commonly followed by increased anxiety, insomnia, loss of appetite, migraine, irritability, restlessness and other physical and psychological signs. Tolerance to cannabis and cannabis withdrawal symptoms are believed to be the result of the desensitization of CB1 receptors by THC.
CASE SUMMARY
This report describes the case of a 19-year-old woman with cannabis withdrawal syndrome treated with cannabidiol (CBD) for 10 days. Daily symptom assessments demonstrated the absence of significant withdrawal, anxiety and dissociative symptoms during the treatment.
WHAT IS NEW AND CONCLUSION
CBD can be effective for the treatment of cannabis withdrawal syndrome.
已知和目的
重度使用者在戒大麻后通常会出现焦虑、失眠、食欲不振、偏头痛、易怒、不安等身体和心理症状。人们认为大麻耐受性和戒大麻症状是由 THC 使 CB1 受体脱敏引起的。
病例概述
本报告描述了一例大麻戒断综合征患者，该患者接受了 CBD 治疗 10 天。每日症状评估表明，在治疗过程中，患者没有明显的戒断、焦虑和分离症状。
新内容和结论
CBD 可有效治疗大麻戒断综合征。
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