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牛奶与胰岛素依赖型糖尿病:二者有关联吗?

Cow milk and insulin-dependent diabetes mellitus: is there a relationship?

作者信息

Scott F W

机构信息

Nutrition Research Division Food Directorate, Health & Welfare Canada, Ottawa Ontario.

出版信息

Am J Clin Nutr. 1990 Mar;51(3):489-91. doi: 10.1093/ajcn/51.3.489.

DOI:10.1093/ajcn/51.3.489
PMID:2309656
Abstract

Various cow-milk preparations have, with some variation, been reported to be diabetogenic in two animal models of insulin-dependent diabetes mellitus (IDDM), the BioBreeding (BB) rat and the nonobese diabetic (NOD) mouse. However, the suggestion of an inverse relationship between breast-feeding and IDDM based on epidemiological studies, remains controversial. There is a significant positive correlation between consumption of unfermented milk protein and incidence of IDDM in data from various countries. Conversely, a possible negative relationship is observed between breast-feeding at age 3 mo and IDDM risk. Diet may be an important permissive factor in the development of IDDM.

摘要

据报道,在两种胰岛素依赖型糖尿病(IDDM)动物模型,即生物繁殖(BB)大鼠和非肥胖糖尿病(NOD)小鼠中,各种牛奶制品在致糖尿病方面存在一些差异。然而,基于流行病学研究得出的母乳喂养与IDDM呈负相关的观点仍存在争议。在来自不同国家的数据中,未发酵乳蛋白的摄入量与IDDM的发病率之间存在显著的正相关。相反,在3个月大时进行母乳喂养与IDDM风险之间观察到可能的负相关关系。饮食可能是IDDM发病的一个重要促成因素。

相似文献

1
Cow milk and insulin-dependent diabetes mellitus: is there a relationship?牛奶与胰岛素依赖型糖尿病:二者有关联吗?
Am J Clin Nutr. 1990 Mar;51(3):489-91. doi: 10.1093/ajcn/51.3.489.
2
Dietary cow's milk protein does not alter the frequency of diabetes in the BB rat.饮食中的牛乳蛋白不会改变BB大鼠患糖尿病的频率。
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3
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AAP recommendations on cow milk, soy, and early infant feeding.美国儿科学会关于牛奶、大豆及婴儿早期喂养的建议。
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[Is the drinking of cow milk in infancy a predisposing factor for insulin-dependent diabetes mellitus?].
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Cow's milk-free diet does not prevent diabetes in NOD mice.不含牛奶的饮食不能预防非肥胖糖尿病(NOD)小鼠患糖尿病。
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Cow milk feeding induces antibodies to insulin in children--a link between cow milk and insulin-dependent diabetes mellitus?牛奶喂养会诱导儿童产生胰岛素抗体——牛奶与胰岛素依赖型糖尿病之间存在关联?
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Type I (insulin-dependent) diabetes mellitus and cow milk: casein variant consumption.I型(胰岛素依赖型)糖尿病与牛奶:酪蛋白变体的摄入
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IDDM and milk consumption. A case-control study in São Paulo, Brazil.胰岛素依赖型糖尿病与牛奶消费:巴西圣保罗的一项病例对照研究
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J Endocrinol Invest. 1999 Jul-Aug;22(7):568-80. doi: 10.1007/BF03343611.
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Influence of glycation on cis/trans isomerization and tautomerization in novel morphiceptin-related Amadori compounds.糖基化对新型吗啡肽相关阿玛多利化合物顺式/反式异构化和互变异构的影响。
Glycoconj J. 1998 Jun;15(6):563-70. doi: 10.1023/a:1006907724915.
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A model for the involvement of MHC class II proteins in the development of type 1 (insulin-dependent) diabetes mellitus in response to bovine serum albumin peptides.一种关于MHC II类蛋白在对牛血清白蛋白肽产生反应的1型(胰岛素依赖型)糖尿病发展过程中所起作用的模型。
Diabetologia. 1993 Apr;36(4):364-8. doi: 10.1007/BF00400243.
7
Diet, cow's milk protein antibodies and the risk of IDDM in Finnish children. Childhood Diabetes in Finland Study Group.饮食、牛奶蛋白抗体与芬兰儿童患胰岛素依赖型糖尿病的风险。芬兰儿童糖尿病研究小组。
Diabetologia. 1994 Apr;37(4):381-7. doi: 10.1007/s001250050121.
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Is breast feeding beneficial in the UK? Statement of the standing Committee on Nutrition of the British Paediatric Association.在英国母乳喂养有益吗?英国儿科学会营养常务委员会声明。
Arch Dis Child. 1994 Oct;71(4):376-80. doi: 10.1136/adc.71.4.376.
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Epidemiology of childhood diabetes mellitus in Finland--background of a nationwide study of type 1 (insulin-dependent) diabetes mellitus. The Childhood Diabetes in Finland (DiMe) Study Group.芬兰儿童糖尿病的流行病学——一项关于1型(胰岛素依赖型)糖尿病全国性研究的背景。芬兰儿童糖尿病(DiMe)研究小组。
Diabetologia. 1992 Jan;35(1):70-6. doi: 10.1007/BF00400854.
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Disease-associated anti-bovine serum albumin antibodies in type 1 (insulin-dependent) diabetes mellitus are detected by particle concentration fluoroimmunoassay, and not by enzyme linked immunoassay.1型(胰岛素依赖型)糖尿病中与疾病相关的抗牛血清白蛋白抗体通过颗粒浓度荧光免疫测定法检测,而非酶联免疫测定法。
Diabetologia. 1992 Oct;35(10):985-90. doi: 10.1007/BF00401430.