Suppr超能文献

具有不同免疫丧失率的恢复后时间模型。

A time since recovery model with varying rates of loss of immunity.

机构信息

Department of Biology, University of Utah, Salt Lake City, UT 84112, USA.

出版信息

Bull Math Biol. 2012 Dec;74(12):2810-9. doi: 10.1007/s11538-012-9780-7. Epub 2012 Oct 25.

Abstract

For many infectious diseases, immunity wanes over time. The majority of SIRS models assume that this loss of immunity takes place at a constant rate. We study temporary immunity within a SIRS model structure if the rate of loss of immunity can depend on the time since recovery from disease. We determine the conditions under which the endemic steady state becomes unstable and periodic oscillations set in, showing that a fairly rapid change between slow and rapid immunity loss is necessary to produce oscillations.

摘要

对于许多传染病来说,免疫力会随着时间的推移而减弱。大多数 SIRS 模型假设这种免疫力的丧失是按恒定速率发生的。如果免疫丧失的速率可以依赖于从疾病中恢复的时间,我们就在 SIRS 模型结构内研究暂时免疫力。我们确定了地方病稳定状态变得不稳定并出现周期性振荡的条件,表明在缓慢和快速免疫丧失之间快速变化是产生振荡所必需的。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验