The Centre de Recherche Institut Universitaire en Santé Mentale de Québec-CRIUSMQ, Laval University, Québec G1J 2G3, Canada.
J Neurosci Methods. 2013 Jan 30;212(2):237-41. doi: 10.1016/j.jneumeth.2012.10.008. Epub 2012 Oct 22.
Parallel electrophysiological recording and behavioral monitoring of freely moving animals is essential for a better understanding of the neural mechanisms underlying behavior. In this paper we describe a novel wireless recording technique, which is capable of synchronously recording in vivo multichannel electrophysiological (LFP, MUA, EOG, EMG) and activity data (accelerometer, video) from freely moving cats. The method is based on the integration of commercially available components into a simple monitoring system and is complete with accelerometers and the needed signal processing tools. LFP activities of freely moving group-housed cats were recorded from multiple intracortical areas and from the hippocampus. EMG, EOG, accelerometer and video were simultaneously acquired with LFP activities 24-h a day for 3 months. These recordings confirm the possibility of using our wireless method for 24-h long-term monitoring of neurophysiological and behavioral data of freely moving experimental animals such as cats, ferrets, rabbits and other large animals.
为了更好地理解行为背后的神经机制，对自由活动动物进行并行的电生理记录和行为监测至关重要。本文介绍了一种新的无线记录技术，该技术能够从自由活动的猫中同步记录多通道电生理（LFP、MUA、EOG、EMG）和活动数据（加速度计、视频）。该方法基于将市售组件集成到一个简单的监测系统中，并配备了加速度计和所需的信号处理工具。从多个皮层区域和海马体记录了群居自由活动的猫的 LFP 活动。EMG、EOG、加速度计和视频与 LFP 活动一起 24 小时不间断地同步采集，持续 3 个月。这些记录证实了我们的无线方法可用于 24 小时长期监测自由活动实验动物（如猫、雪貂、兔子和其他大型动物）的神经生理和行为数据。
