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三尖瓣布鲁氏菌性心内膜炎:一例报告并文献复习

Brucellar Endocarditis of the Tricuspid Valve: A Case Report and Review of the Literature.

作者信息

Boumis Evangelo, Chinello Pierangelo, Galati Vincenzo, Topino Simone, Gavaruzzi Francesca, Cicalini Stefania

机构信息

Clinical Infectious Diseases Department, National Institute for Infectious Diseases "Lazzaro Spallanzani", IRCCS, 00149 Rome, Italy.

出版信息

Pathogens. 2024 Mar 8;13(3):239. doi: 10.3390/pathogens13030239.

Abstract

Brucellar endocarditis is a rare entity commonly described as a severe disease associated with high mortality and generally requiring valve surgery for cure. Right-sided endocarditis, a very uncommon presentation of brucellosis, may be associated with a better prognosis. We describe the case of a 72-year-old woman admitted to our institution with a persistent fever and multiple pulmonary infiltrates. Transthoracic echocardiography and serologic tests led to the diagnosis of brucellar tricuspid endocarditis. The patient responded favorably to antibiotic treatment alone and did not need surgery. Prolonged antibiotic therapy with a combination of drugs active on intracellular microorganisms in the absence of surgical treatment could be effective in brucellar tricuspid endocarditis when the valve is not severely damaged.

摘要

布鲁氏菌性心内膜炎是一种罕见病症,通常被描述为一种与高死亡率相关的严重疾病,一般需要进行瓣膜手术才能治愈。右侧心内膜炎是布鲁氏菌病一种非常罕见的表现形式,其预后可能较好。我们报告一例72岁女性患者,因持续发热和多处肺部浸润入住我院。经胸超声心动图检查和血清学检测确诊为布鲁氏菌性三尖瓣心内膜炎。该患者仅接受抗生素治疗即取得良好疗效,无需手术。对于瓣膜未严重受损的布鲁氏菌性三尖瓣心内膜炎,在不进行手术治疗的情况下,联合使用对细胞内微生物有效的药物进行长时间抗生素治疗可能有效。

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本文引用的文献

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The European Union One Health 2022 Zoonoses Report.《欧盟2022年人畜共患病“同一个健康”报告》
EFSA J. 2023 Dec 12;21(12):e8442. doi: 10.2903/j.efsa.2023.8442. eCollection 2023 Dec.
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Endocarditis in Persons Who Inject Drugs.注射毒品者的心内膜炎
Open Forum Infect Dis. 2020 Feb 18;7(4):ofaa063. doi: 10.1093/ofid/ofaa063. eCollection 2020 Apr.
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[Clinical features of 9 cases of Brucella endocarditis].9例布鲁氏菌性心内膜炎的临床特征
Zhonghua Xin Xue Guan Bing Za Zhi. 2020 Feb 24;48(2):142-147. doi: 10.3760/cma.j.issn.0253-3758.2020.02.010.
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Trends of human brucellosis in Italy, 1998-2010.1998-2010 年意大利人间布鲁氏菌病流行趋势。
Epidemiol Infect. 2014 Jun;142(6):1188-95. doi: 10.1017/S0950268813002227. Epub 2013 Sep 18.
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Medical versus medical and surgical treatment for brucella endocarditis.医学与医学和手术治疗布氏杆菌性心内膜炎。
Ann Thorac Surg. 2012 Dec;94(6):2141-6. doi: 10.1016/j.athoracsur.2012.07.006. Epub 2012 Oct 26.
10
Management of Brucella endocarditis: results of the Gulhane study.布鲁氏菌性心内膜炎的治疗:Gulhane 研究的结果。
Int J Antimicrob Agents. 2012 Aug;40(2):145-50. doi: 10.1016/j.ijantimicag.2012.04.009. Epub 2012 Jun 21.

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