Boumis Evangelo, Chinello Pierangelo, Galati Vincenzo, Topino Simone, Gavaruzzi Francesca, Cicalini Stefania
Clinical Infectious Diseases Department, National Institute for Infectious Diseases "Lazzaro Spallanzani", IRCCS, 00149 Rome, Italy.
Pathogens. 2024 Mar 8;13(3):239. doi: 10.3390/pathogens13030239.
Brucellar endocarditis is a rare entity commonly described as a severe disease associated with high mortality and generally requiring valve surgery for cure. Right-sided endocarditis, a very uncommon presentation of brucellosis, may be associated with a better prognosis. We describe the case of a 72-year-old woman admitted to our institution with a persistent fever and multiple pulmonary infiltrates. Transthoracic echocardiography and serologic tests led to the diagnosis of brucellar tricuspid endocarditis. The patient responded favorably to antibiotic treatment alone and did not need surgery. Prolonged antibiotic therapy with a combination of drugs active on intracellular microorganisms in the absence of surgical treatment could be effective in brucellar tricuspid endocarditis when the valve is not severely damaged.
布鲁氏菌性心内膜炎是一种罕见病症,通常被描述为一种与高死亡率相关的严重疾病,一般需要进行瓣膜手术才能治愈。右侧心内膜炎是布鲁氏菌病一种非常罕见的表现形式,其预后可能较好。我们报告一例72岁女性患者,因持续发热和多处肺部浸润入住我院。经胸超声心动图检查和血清学检测确诊为布鲁氏菌性三尖瓣心内膜炎。该患者仅接受抗生素治疗即取得良好疗效,无需手术。对于瓣膜未严重受损的布鲁氏菌性三尖瓣心内膜炎,在不进行手术治疗的情况下,联合使用对细胞内微生物有效的药物进行长时间抗生素治疗可能有效。