VISN-6 Mental Illness Research & Education Center, Durham, NC 27705, USA.
Depress Anxiety. 2012 Dec;29(12):1032-42. doi: 10.1002/da.22012. Epub 2012 Oct 26.
This study was designed to examine the concordance of proposed DSM-V posttraumatic stress disorder (PTSD) criteria with DSM-IV classification rules and examine the impact of the proposed DSM-V PTSD criteria on prevalence.
The sample (N = 185) included participants who were recruited for studies focused on trauma and health conducted at an academic medical center and VA medical center in the southeastern United States. The prevalence and concordance between DSM-IV and the proposed DSM-V classifications were calculated based on results from structured clinical interviews. Prevalence rates and diagnostic efficiency indices including sensitivity, specificity, area under the curve (AUC), and Kappa were calculated for each of the possible ways to define DSM-V PTSD.
Ninety-five percent of the sample reported an event that met both DSM-IV PTSD Criterion A1 and A2, but only 89% reported a trauma that met Criterion A on DSM-V. Results examining concordance between DSM-IV and DSM-V algorithms indicated that several of the algorithms had AUCs above 0.90. The requirement of two symptoms from both Clusters D and E provided strong concordance to DSM-IV (AUC = 0.93; Kappa = 0.86) and a greater balance between sensitivity and specificity than requiring three symptoms in both Clusters D and E.
Despite several significant changes to the diagnostic criteria for PTSD for DSM-V, several possible classification rules provided good concordance with DSM-IV. The magnitude of the impact of DSM-V decision rules on prevalence will be largely affected by the DSM-IV PTSD base rate in the population of interest.
本研究旨在检验 DSM-V 创伤后应激障碍(PTSD)诊断标准与 DSM-IV 分类规则的一致性,并探讨 DSM-V PTSD 诊断标准对患病率的影响。
该样本(N=185)包括在美国东南部的一所学术医疗中心和退伍军人事务医疗中心参加以创伤和健康为主题的研究的参与者。根据结构化临床访谈的结果,计算了 DSM-IV 和拟议的 DSM-V 分类之间的患病率和一致性。计算了每种可能的 DSM-V PTSD 定义方法的患病率和诊断效率指数,包括敏感性、特异性、曲线下面积(AUC)和 Kappa。
95%的样本报告了符合 DSM-IV PTSD 标准 A1 和 A2 的事件,但只有 89%的样本报告了符合 DSM-V A 标准的创伤。检查 DSM-IV 和 DSM-V 算法之间一致性的结果表明,几种算法的 AUC 高于 0.90。从簇 D 和 E 中各选择两个症状的要求与 DSM-IV 具有很强的一致性(AUC=0.93;Kappa=0.86),并且在簇 D 和 E 中都要求三个症状的敏感性和特异性之间达到了更好的平衡。
尽管 DSM-V 对 PTSD 的诊断标准进行了一些重大修改,但一些可能的分类规则与 DSM-IV 具有很好的一致性。DSM-V 决策规则对患病率的影响程度将在很大程度上受到感兴趣人群中 DSM-IV PTSD 的基础患病率的影响。