Mehrabian Aa, Esna-Ashari F, Zham H, Hadizadeh M, Bohlooli M, Khayamzadeh M, Akbari Me
Cancer Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran.
Iran J Public Health. 2010;39(3):27-31. Epub 2010 Sep 30.
Gastric cancer is a common and lethal disease throughout the world. In Iran with 7300 new cases annually, it is the first cause of cancer related death in both sexes. Regarding the high incidence (10.5/100000 individuals) of gastric cancer and priority of prevalence index in cancer management, in this study we tried to determine 1, 2-3 and 4-5 year point prevalence of the disease according to survival data.
Survival and incidence data were used for determination of cancer prevalence. Incidence data were extracted from cancer registry in Iran and survival data were determined in a descriptive study by following up 3439 gastric cancer patients in Cancer Research Center (CRC). 1, 2-3 and 4-5 year prevalence was estimated from incidence rates in different years and the proportion of patients surviving 0.5, 1.5, 2.5, 3.5 and 4.5 years from the time of diagnosis.
patients with survival of 0.5, 1.5, 2.5, 3.5 and 4.5 years from the time of diagnosis were 46.38%, 26 %, 19.36%, 15.47% and 12.8% respectively. The prevalence of 1, 2-3 and 4-5 year was 3392, 3118and 1824 respectively. The cumulative 5 year prevalence was 8334 cases.
These estimates of the point prevalence of gastric cancer at 1, 2-3 and 4-5 years are applicable to the evaluation of initial treatment, clinical follow-up, and point of cure. Therefore 1, 2-3 and 4-5 year point prevalence estimates, are necessary in health service planning for gastric cancer management and should be considered by public health managers.
胃癌是一种在全球范围内常见且致命的疾病。在伊朗,每年有7300例新发病例,是男女癌症相关死亡的首要原因。鉴于胃癌的高发病率(每10万人中有10.5例)以及癌症管理中患病率指数的优先性,在本研究中,我们试图根据生存数据确定该疾病1年、2 - 3年和4 - 5年的时点患病率。
生存和发病数据用于确定癌症患病率。发病数据从伊朗癌症登记处提取,生存数据通过对癌症研究中心(CRC)的3439例胃癌患者进行随访的描述性研究来确定。根据不同年份的发病率以及从诊断时间起存活0.5年、1.5年、2.5年、3.5年和4.5年的患者比例来估计1年、2 - 3年和4 - 5年的患病率。
从诊断时间起存活0.5年、1.5年、2.5年、3.5年和4.5年的患者比例分别为46.38%、26%、19.36%、15.47%和12.8%。1年、2 - 3年和4 - 5年的患病率分别为3392、3118和1824。5年累计患病率为8334例。
这些对胃癌1年、2 - 3年和4 - 5年时点患病率的估计适用于初始治疗评估、临床随访和治愈点评估。因此,1年、2 - 3年和4 - 5年时点患病率估计对于胃癌管理的卫生服务规划是必要的,公共卫生管理人员应予以考虑。