Hassanzade J, Molavi E Vardanjani H, Farahmand M, Rajaiifard A R
Department of Epidemiology, Shiraz University of Medical Sciences, Shiraz, Iran.
Deputy of Health, Chronic Disease Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran J Cancer Prev. 2011 Fall;4(4):163-9.
Considering the importance of updating information about incidence and mortality of common or fatal cancers and the need for studying the effectiveness of changes in the Iranian cancer registration system from pathological based to population based since 2007, the aim of this study was to provide updated population based information on incidence and mortality rates of esophagus, stomach, colon and rectum cancers in south of Iran , and also to provide basic data for investigating the performance of population based cancer registration system in these regions.
This study was a review of population based data of esophagus, stomach, colon and rectum cancers in Fars province during 2008-9.We estimated Age Standardized Incidence and Mortality Rates (ASIRs and ASMRs), truncated ASIRs and ASMRs for each cancer using direct age standardization based on Iran's population and also based on the standard population of world.Finally, considering poison distribution, we calculated standard error of incidenceand mortality rates.
Adjusted incidence rates of esophagus, stomach, colon and rectum cancers(per 100,000) and their standard error were 2.56(0.0092), 9.99(0.0182),4.85(0.0127) and 1.56(0.0072) in males; and 1.60(0.0072), 4.66 (0.0123),3.24(0.0103) and 0.93(0.0055) in females respectively. These values for ASMRs per 100000 were 0.94(0.0056), 11.54(0.0195), 2.46(0.009), 0.34(0.0033) for men, and 0.51(0.004), 4.21(0.0117), 1.54(0.0071) and 0.41(0.0037) for women.
Incidence and mortality rates of esophagus cancer in southern regions of Iran were less than the national average. We also clarified that stomach and colorectal cancers were the most important digestive cancers in this area.
鉴于更新常见或致命癌症发病率和死亡率信息的重要性，以及自2007年以来研究伊朗癌症登记系统从基于病理到基于人群的变化效果的必要性，本研究的目的是提供伊朗南部食管癌、胃癌、结肠癌和直肠癌发病率和死亡率的最新基于人群的信息，并为调查这些地区基于人群的癌症登记系统的性能提供基础数据。
本研究回顾了2008 - 2009年法尔斯省食管癌、胃癌、结肠癌和直肠癌的基于人群的数据。我们使用基于伊朗人口以及基于世界标准人口的直接年龄标准化方法，估计了每种癌症的年龄标准化发病率和死亡率（ASIRs和ASMRs）、截断ASIRs和ASMRs。最后，考虑泊松分布，我们计算了发病率和死亡率的标准误差。
男性食管癌、胃癌、结肠癌和直肠癌的调整发病率（每100,000）及其标准误差分别为2.56(0.0092)、9.99(0.0182)、4.85(0.0127)和1.56(0.0072)；女性分别为1.60(0.0072)、4.66(0.0123)、3.24(0.0103)和0.93(0.0055)。每100000的ASMRs值男性为0.94(0.0056)、11.54(0.0195)、2.46(0.009)、0.34(0.0033)，女性为0.51(0.004)、4.21(0.0117)、1.54(0.0071)和0.41(0.0037)。
伊朗南部地区食管癌的发病率和死亡率低于全国平均水平。我们还明确了胃癌和结直肠癌是该地区最重要的消化系统癌症。
