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肺挫伤和连枷胸的处理:东部创伤外科学会实践管理指南。

Management of pulmonary contusion and flail chest: an Eastern Association for the Surgery of Trauma practice management guideline.

机构信息

Division of Trauma and Critical Care, University of Massachusetts Medical Center, Worcester, Massachusetts, USA.

出版信息

J Trauma Acute Care Surg. 2012 Nov;73(5 Suppl 4):S351-61. doi: 10.1097/TA.0b013e31827019fd.

Abstract

BACKGROUND

Despite the prevalence and recognized association of pulmonary contusion and flail chest (PC-FC) as a combined, complex injury pattern with interrelated pathophysiology, the mortality and morbidity of this entity have not improved during the last three decades. The purpose of this updated EAST practice management guideline was to present evidence-based recommendations for the treatment of PC-FC.

METHODS

A query was conducted of MEDLINE, Embase, PubMed and Cochrane databases for the period from January 1966 through June 30, 2011. All evidence was reviewed and graded by two members of the guideline committee. Guideline formulation was performed by committee consensus.

RESULTS

Of the 215 articles identified in the search, 129 were deemed appropriate for review, grading, and inclusion in the guideline. This practice management guideline has a total of six Level 2 and eight Level 3 recommendations.

CONCLUSION

Patients with PC-FC should not be excessively fluid restricted but should be resuscitated to maintain signs of adequate tissue perfusion. Obligatory mechanical ventilation in the absence of respiratory failure should be avoided. The use of optimal analgesia and aggressive chest physiotherapy should be applied to minimize the likelihood of respiratory failure. Epidural catheter is the preferred mode of analgesia delivery in severe flail chest injury. Paravertebral analgesia may be equivalent to epidural analgesia and may be appropriate in certain situations when epidural is contraindicated.A trial of mask continuous positive airway pressure should be considered in alert patients with marginal respiratory status. Patients requiring mechanical ventilation should be supported in a manner based on institutional and physician preference and separated from the ventilator at the earliest possible time. Positive end-expiratory pressure or continuous positive airway pressure should be provided. High-frequency oscillatory ventilation should be considered for patients failing conventional ventilatory modes. Independent lung ventilation may also be considered in severe unilateral pulmonary contusion when shunt cannot be otherwise corrected.Surgical fixation of flail chest may be considered in cases of severe flail chest failing to wean from the ventilator or when thoracotomy is required for other reasons. Self-activating multidisciplinary protocols for the treatment of chest wall injuries may improve outcome and should be considered where feasible.Steroids should not be used in the therapy of pulmonary contusion. Diuretics may be used in the setting of hydrostatic fluid overload in hemodynamically stable patients or in the setting of known concurrent congestive heart failure.

摘要

背景

尽管肺挫伤和连枷胸(PC-FC)作为一种具有相互关联的病理生理学的联合复杂损伤模式普遍存在并已被公认,但在过去三十年中,这种疾病的死亡率和发病率并未改善。本 EAST 实践管理指南的目的是提出治疗 PC-FC 的循证建议。

方法

对 MEDLINE、Embase、PubMed 和 Cochrane 数据库进行了 1966 年 1 月至 2011 年 6 月 30 日期间的查询。两名指南委员会成员对所有证据进行了审查和分级。通过委员会共识制定了指南草案。

结果

在搜索中确定的 215 篇文章中,有 129 篇被认为适合审查、分级和纳入指南。本实践管理指南共有六项 2 级和八项 3 级建议。

结论

不应过度限制 PC-FC 患者的液体摄入,而应复苏以维持足够组织灌注的迹象。在没有呼吸衰竭的情况下,应避免强制性机械通气。应使用最佳的镇痛和积极的胸部物理疗法来最大程度地减少呼吸衰竭的可能性。在严重连枷胸损伤中,硬膜外导管是首选的镇痛输送方式。椎旁镇痛可能与硬膜外镇痛等效,并且在硬膜外禁忌的某些情况下可能是合适的。对于呼吸状态临界的清醒患者,应考虑试用面罩持续气道正压通气。需要机械通气的患者应根据机构和医生的偏好进行支持,并在尽可能早的时间与呼吸机分离。应提供呼气末正压或持续气道正压。对于常规通气模式失败的患者,应考虑高频振荡通气。在无法纠正分流的情况下,严重单侧肺挫伤也可考虑独立肺通气。对于未能从呼吸机上脱机或因其他原因需要开胸手术的严重连枷胸患者,可考虑进行连枷胸固定手术。用于治疗胸壁损伤的自激活多学科方案可能会改善结果,在可行的情况下应考虑使用。不应在肺挫伤的治疗中使用类固醇。在血流动力学稳定的患者中存在静水力学液体超负荷或已知并发充血性心力衰竭的情况下,可以使用利尿剂。

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