ERA–EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Nephrol Dial Transplant. 2012 Oct;27 Suppl 3:iii32-8. doi: 10.1093/ndt/gfs113.
Chronic kidney disease (CKD) is becoming a major public health issue worldwide and an important contributor to the overall non-communicable disease burden. It is associated with major serious consequences including increased risk of mortality, end-stage renal disease, accelerated cardiovascular disease (CVD), mineral and bone disease, adverse metabolic and nutritional consequences, infections, reduced cognitive function and increased risk of acute kidney injury. Mortality from CVD is estimated to be at least 8- to 10-fold higher in CKD subjects compared to non-CKD subjects. Estimates from different parts of the world, especially large countries, reveal an increasing incidence and prevalence of CKD. This is partly attributed to the global increasing prevalence of diabetes, hypertension, obesity and CVD. The global economic impact of CKD is tremendous. This calls for the need of a global effort to raise awareness of CKD, to incorporate prevention of CKD progression program in the public health agenda and to implement programs for early screening and detection of CKD, especially in high-risk population so to allow early institution of treatment to prevent further CKD progression. Hopefully, by doing so, we may reduce CKD burden globally over time and, most importantly, improve the health outcomes of patients with CKD.
慢性肾脏病（CKD）正在成为全球主要的公共卫生问题，也是导致非传染性疾病总负担的重要因素。它与多种严重后果相关，包括死亡率增加、终末期肾病、加速心血管疾病（CVD）、矿物质和骨疾病、不良代谢和营养后果、感染、认知功能降低以及急性肾损伤风险增加。与非 CKD 患者相比，CKD 患者的 CVD 死亡率估计至少高出 8 至 10 倍。来自世界各地的估计，尤其是大国的估计，揭示了 CKD 的发病率和患病率呈上升趋势。这部分归因于全球糖尿病、高血压、肥胖和 CVD 的流行率不断上升。CKD 对全球经济的影响是巨大的。因此，需要全球共同努力提高对 CKD 的认识，将预防 CKD 进展的计划纳入公共卫生议程，并实施早期筛查和检测 CKD 的计划，特别是在高危人群中，以便及早开始治疗，防止 CKD 进一步进展。希望通过这样做，我们可以随着时间的推移减轻全球 CKD 的负担，最重要的是，改善 CKD 患者的健康结果。
