Noh Jung-Mun, Lee Seock-Hwan, Kim Hyun-Woo, Yang Hong-Seok
Department of Family Medicine, Daegu Medical Center, Daegu, Korea.
Korean J Fam Med. 2012 Sep;33(5):305-10. doi: 10.4082/kjfm.2012.33.5.305. Epub 2012 Sep 27.
Smoking and obesity are known risk factors for cardiovascular diseases, while low serum levels of high density lipoprotein-cholesterol is an independent risk factor for mortality from ischemic heart diseases. This study examines changes in the serum level of high density lipoprotein-cholesterol depending on changes in the state of smoking and body mass index.
A survey and blood check-up were conducted on medical examination, along with acts of smoking among male adults of 25 years or older who visited the health promotion center of Daegu Medical Center from 2007 to 2010, and the results were analyzed. The subjects were divided into two different groups, current smokers and abstainers, and body mass index, total cholesterol, high density lipoprotein-cholesterol, low density lipoprotein-cholesterol, and triglycerides for three years were compared in both groups. Changes between the first and second visits in body mass index and lipid profiles of the two groups were compared to analyze changes after abstaining.
The subject group which showed a significant increase in high density lipoprotein-cholesterol level was only abstainers whose body mass index had decreased by more than 0.5 kg/m(2).
Smoking cessation increases serum levels of high density lipoprotein-cholesterol. If reduction of body mass index and smoking cessation are combined, the risk of cardiovascular disease will be lower in proportion to the increase in serum high density lipoprotein.
吸烟和肥胖是已知的心血管疾病风险因素，而血清高密度脂蛋白胆固醇水平低是缺血性心脏病死亡的独立风险因素。本研究根据吸烟状态和体重指数的变化，研究血清高密度脂蛋白胆固醇水平的变化。
对2007年至2010年访问大邱医疗中心健康促进中心的25岁及以上男性成年人进行医学检查、调查和血液检查，并分析吸烟行为，对结果进行分析。将受试者分为当前吸烟者和戒烟者两组，比较两组三年来的体重指数、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和甘油三酯。比较两组第一次和第二次就诊时体重指数和血脂谱的变化，以分析戒烟后的变化。
高密度脂蛋白胆固醇水平显著升高的受试者组仅为体重指数下降超过0.5kg/m²的戒烟者。
戒烟可提高血清高密度脂蛋白胆固醇水平。如果将体重指数降低和戒烟相结合，心血管疾病风险将随着血清高密度脂蛋白的增加而成比例降低。
