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本文引用的文献

1
Insulin resistance in subjects with a history of thyrotoxic periodic paralysis (TPP).有甲状腺毒症性周期性麻痹(TPP)病史的受试者的胰岛素抵抗
Clin Endocrinol (Oxf). 2009 May;70(5):794-7. doi: 10.1111/j.1365-2265.2008.03395.x. Epub 2008 Aug 28.
2
Thyrotoxic periodic paralysis in a Hispanic man after the administration of prednisone.一名西班牙裔男性在服用泼尼松后发生甲状腺毒症性周期性麻痹。
Endocr Pract. 2006 Jul-Aug;12(4):427-31. doi: 10.4158/EP.12.4.427.
3
Clinical review: Thyrotoxic periodic paralysis: a diagnostic challenge.临床综述:甲状腺毒症性周期性瘫痪:一项诊断挑战。
J Clin Endocrinol Metab. 2006 Jul;91(7):2490-5. doi: 10.1210/jc.2006-0356. Epub 2006 Apr 11.
4
Levothyroxine: therapeutic use and regulatory issues related to bioequivalence.左甲状腺素:与生物等效性相关的治疗用途及监管问题
Expert Opin Pharmacother. 2002 Jun;3(6):727-32. doi: 10.1517/14656566.3.6.727.
5
Bioequivalence of generic and brand-name levothyroxine products in the treatment of hypothyroidism.通用型和品牌型左甲状腺素产品在治疗甲状腺功能减退症方面的生物等效性。
JAMA. 1997 Apr 16;277(15):1205-13.
6
Thyrotoxic periodic paralysis in a Chinese population.中国人群中的甲状腺毒症性周期性瘫痪
QJM. 1996 Jun;89(6):463-8. doi: 10.1093/qjmed/89.6.463.

左甲状腺素和泼尼松导致一名中年男子全身无力。

Levothyroxine and prednisone causing generalized weakness in a middle-aged man.

作者信息

Word Andrew, Davidson Kevin, Elsayed Essam

机构信息

Departement of Internal Medicine, UT Southwestern Medical School, 5323 Harry Hines Blvd., Dallas, TX 75390, USA.

出版信息

Case Rep Endocrinol. 2012;2012:616930. doi: 10.1155/2012/616930. Epub 2012 Oct 18.

DOI:10.1155/2012/616930
PMID:23119192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3483653/
Abstract

Thyrotoxic induced hypokalemic periodic paralysis is a rare disorder that had been described in middle-aged men, predominantly Asians and Hispanics. This case presented with generalized weakness and hypokalemia after changing prescription for levothyroxine and starting prednisone to treat upper respiratory infection in a previously asymptomatic middle-aged Hispanic male. In this paper, we will go over the clinical presentation, mechanisms, and treatment of thyrotoxic induced hypokalemic periodic paralysis. Our objectives are to identify the classic constellation of findings in thyrotoxic periodic paralysis and to recognize the importance of considering thyrotoxic periodic paralysis among patients with hypokalemia.

摘要

甲状腺毒症性低钾性周期性麻痹是一种罕见的疾病,多见于中年男性,主要是亚洲人和西班牙裔。该病例为一名既往无症状的中年西班牙裔男性,在更改左甲状腺素处方并开始使用泼尼松治疗上呼吸道感染后,出现全身无力和低钾血症。在本文中,我们将阐述甲状腺毒症性低钾性周期性麻痹的临床表现、发病机制及治疗方法。我们的目标是明确甲状腺毒症性周期性麻痹的典型症状组合,并认识到在低钾血症患者中考虑甲状腺毒症性周期性麻痹的重要性。