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增生性念珠菌病 - 右侧口腔、扁桃体、下咽和喉部。

Hyperplastic candidiasis - right-oral cavity, tonsil hypopharynx and larynx.

作者信息

Chourdia V

机构信息

Honorary Consultant Otolaryngologist, Geeta Bhavan and Guru Teg-Bahadur Hospitals, 11, Anoop Nagar, 8 Indore.

出版信息

Indian J Otolaryngol Head Neck Surg. 2001 Jul;53(3):244-7. doi: 10.1007/BF03028567.

Abstract

A twenty five year old female, presented with burning in throat, Odynophagia and characteristic history of falling of granules, He had a verrucous type granular lesion right retromolar area., tonsil & its fossa, Lingual Surface Epiglottis & Hypoharyngeal wall, Right Aryepiglottic fold & ventricular fold Oedmatous and Scattered granules on both vocal folds & right Posterolateral border of tongue. Candida was detected in 10% Potassium Hydroxide, gram stained smear, prepared from tissue scrapping. Histopathology report of excised specimen was Fungal Granuloma. She was immunocompetent & was otherwise normal. Disease could possibly be attributed to virulence attributes of Candida. This hyperplastic candidiasis was combinedly treated with surgical excision and oral daily 100mg, fluconazole for six weeks, with Elevan months of follow-up. This is indeed a very rare case & only very few such cases, are reported so far in literature.

摘要

一名25岁女性,出现咽喉部烧灼感、吞咽痛以及颗粒状物脱落的特征性病史。其右磨牙后区、扁桃体及其隐窝、会厌舌面及下咽壁、右杓会厌襞及室襞有疣状颗粒性病变,双侧声带及舌右侧后缘有水肿及散在颗粒。从组织刮片中制备的10%氢氧化钾革兰染色涂片检测到念珠菌。切除标本的组织病理学报告为真菌性肉芽肿。她免疫功能正常,其他方面也正常。该疾病可能归因于念珠菌的毒力特性。这种增生性念珠菌病采用手术切除联合每日口服100毫克氟康唑治疗六周,并进行了11个月的随访。这确实是一个非常罕见的病例,迄今为止文献中仅报道了极少数此类病例。

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本文引用的文献

2
Invasive candidiasis of the tonsil.扁桃体侵袭性念珠菌病
J Laryngol Otol. 1997 Dec;111(12):1199-201. doi: 10.1017/s0022215100139726.
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Fungal infections of the oral cavity.口腔真菌感染
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Fluconazole.氟康唑
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10

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