氨基糖苷类抗生素对人中性粒细胞杀念珠菌活性的抑制作用。
Inhibition of candidacidal activity of human neutrophil leukocytes by aminoglycoside antibiotics.
作者信息
Ferrari F A, Pagani A, Marconi M, Stefanoni R, Siccardi A G
出版信息
Antimicrob Agents Chemother. 1980 Jan;17(1):87-8. doi: 10.1128/AAC.17.1.87.
Abstract
We have tested the effect of five aminoglycoside antibiotics (gentamicin, sisomicin, tobramycin, ribostamycin, and amikacin) on the candidacidal activity of human neutrophils in vitro; all of them are inhibitory and can be grouped into three significantly different levels of toxicity. Gentamicin in the most toxic and sisomicin is the least toxic.
摘要
我们已经在体外测试了五种氨基糖苷类抗生素（庆大霉素、西索米星、妥布霉素、核糖霉素和阿米卡星）对人中性粒细胞杀念珠菌活性的影响；它们均具有抑制作用，并且可分为三种毒性显著不同的水平。庆大霉素毒性最强，西索米星毒性最弱。
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