体外活体染色：其在早期恶性肿瘤检测中的作用
Supravital staining: It's role in detecting early malignancies.
作者信息
Hedge Mahesh Chandra, Kamath Panduranga M, Shreedharan Suja, Dannana Naveen Kumar, Raju Ravikumar M
机构信息
Department of ORLHNS, Kasturba Medical College, Attavara, 575 001 Mangalore, Karnataka India.
出版信息
Indian J Otolaryngol Head Neck Surg. 2006 Jan;58(1):31-4. doi: 10.1007/BF02907735.
Abstract
The efficacy of supravital staining in the detection of malignancies in oro and oropharyngeal lesions and its role in the detection of malignant changes in premalignant lesions were studied. This prospective study comprises 90 cases of clinically suspicious lesions and it was done over a period of 3 years. Most of the patients had multiple risk factors for the development of malignancy. All underwent staining with a modified solution of 1% toluidine blue (TB). In our study the overall sensitivity was 97.29% and the specificity was 62.5%.
摘要
研究了活体外染色在口腔和口咽病变恶性肿瘤检测中的功效及其在癌前病变恶性变化检测中的作用。这项前瞻性研究包括90例临床可疑病变，历时3年完成。大多数患者有多种发生恶性肿瘤的风险因素。所有患者均用改良的1%甲苯胺蓝（TB）溶液进行染色。在我们的研究中，总体敏感性为97.29%，特异性为62.5%。
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