Miniter Una, Bae-Harboe Yoon-Soo Cindy, Powers Jennifer G, Campbell Shannon M, Goldberg Lynne J
Boston University, Boston, Massachusetts, USA.
Dermatol Online J. 2012 Oct 15;18(10):9.
Henoch-Schonlein purpura is an idiopathic, IgA associated, systemic small-vessel vasculitis characterized by the clinical tetrad of palpable purpura, arthralgias, renal dysfunction, and abdominal pain. Whereas Henoch-Schonlein is an overwhelmingly pediatric disease, its rare diagnosis in adults carries a much higher morbidity and mortality.
We describe a 52-year-old man with biopsy proven Henoch-Schonlein who expired from bowel perforation.
Severe gastrointestinal complications and death from gastrointestinal involvement by Henoch-Schonlein purpura is rare. The authors surmise that multiple co-morbidities may have contributed to our patient's demise.
过敏性紫癜是一种特发性、与免疫球蛋白A相关的系统性小血管血管炎，其特征为可触及性紫癜、关节痛、肾功能不全和腹痛这一临床四联征。虽然过敏性紫癜绝大多数是儿科疾病，但在成人中罕见的诊断却伴随着高得多的发病率和死亡率。
我们描述了一名经活检证实为过敏性紫癜的52岁男性，其死于肠穿孔。
过敏性紫癜导致严重胃肠道并发症及因胃肠道受累而死亡的情况很罕见。作者推测多种合并症可能导致了我们这位患者的死亡。
