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甘草细胞培养物的化学成分分析及其与田间种植品种的抗炎比较。

Chemical analysis and anti-inflammatory comparison of the cell culture of Glycyrrhiza with its field cultivated variety.

机构信息

Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China.

出版信息

Food Chem. 2013 Jan 15;136(2):513-7. doi: 10.1016/j.foodchem.2012.08.010. Epub 2012 Aug 17.

DOI:10.1016/j.foodchem.2012.08.010
PMID:23122091
Abstract

Suspended cells of Glycyrrhiza (CG) possessed a similar content of flavonoids and a lower content of triterpenes, when compared with its field cultivated equivalent (NG). Xylene-induced ear oedema and ovalbumin-induced mouse paw oedema were applied, to compare the effects of CG and NG on the acute inflammatory response. Extracts of the cell culture of Glycyrrhiza possessed a similar anti-inflammatory effect to those of NG, through the enhancement of the SOD activity of plasma and liver tissues. The use of a cell culture of liquorice instead of field cultivation would be potentially profitable.

摘要

甘草悬浮细胞的黄酮类化合物含量相似,三萜类化合物含量较低,与其田间栽培品相当。本研究采用二甲苯致小鼠耳肿胀和卵蛋白致小鼠足肿胀模型,比较甘草 CG 和 NG 对急性炎症反应的影响。甘草细胞培养物提取物通过增强血浆和肝组织中超氧化物歧化酶的活性,具有与 NG 相似的抗炎作用。使用甘草细胞培养物代替田间栽培可能具有潜在的经济效益。

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