心力衰竭对老年人睡眠障碍和抑郁症状的影响。
The contribution of heart failure to sleep disturbances and depressive symptoms in older adults.
机构信息
Department of Cardiology, Linköping University Hospital, S-58185 Linköping, Sweden.
出版信息
J Geriatr Psychiatry Neurol. 2012 Sep;25(3):179-87. doi: 10.1177/0891988712458366.
BACKGROUND
The aim of this study was to explore the associations between physical symptoms, sleep disturbances, and depressive symptoms in community-dwelling elderly individuals, comparing persons with and without heart failure (HF).
METHODS
A total of 613 older adults (mean age 78 years) underwent clinical and echocardiographic examinations. Questionnaires were used to evaluate sleep disturbances and depressive symptoms. A model was developed in those with HF (n = 107) and compared with those without HF (n = 506).
RESULTS
Cardiopulmonary symptoms (ie, dyspnea and nighttime palpitations) and pain had significant direct associations with sleep disturbances, which indirectly affected depressive symptoms. The model was essentially the same in those with and without HF except that the effect of sleep disturbances on depressive symptoms was stronger in those with HF (β = 0.64 vs β = 0.45, P = .006).
CONCLUSION
In community-dwelling older adults, regardless of their diagnosis, physical symptoms had a direct effect on sleep disturbances and an indirect effect on depressive symptoms.
背景
本研究旨在探讨社区居住的老年人群中，身体症状、睡眠障碍与抑郁症状之间的关联，比较心力衰竭（HF）患者与非 HF 患者之间的差异。
方法
共有 613 名老年人（平均年龄 78 岁）接受了临床和超声心动图检查。使用问卷评估睡眠障碍和抑郁症状。在 HF 患者（n=107）中建立模型，并与非 HF 患者（n=506）进行比较。
结果
心肺症状（即呼吸困难和夜间心悸）和疼痛与睡眠障碍有显著的直接关联，而睡眠障碍又会间接影响抑郁症状。HF 患者与非 HF 患者的模型基本相同，只是 HF 患者中睡眠障碍对抑郁症状的影响更强（β=0.64 比 β=0.45，P=.006）。
结论
在社区居住的老年人群中，无论是否患有 HF，身体症状都会直接影响睡眠障碍，并通过睡眠障碍间接影响抑郁症状。
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