Prentice A, Vadgama P, Dunlop W
Department of Obstetrics, University of Newcastle upon Tyne, UK.
Intensive Care Med. 1990;16(1):28-32. doi: 10.1007/BF01706321.
The development of lactic acidaemia in the adult forearm in response to partial and total arterial occlusion is described in both plasma and whole blood. Under conditions of total occlusion of the brachial artery lactate levels in the plasma compartment rise at a significantly faster rate; mean difference in gradients -11.6 95% confidence limits -15.6 and -7.6. Thus in these conditions they provide a more sensitive index of tissue hypoxia. Under conditions of partial occlusion there is no significant difference; mean difference in gradients 1.0 95% confidence limits 9.4 and -7.3. Though plasma lactate levels are more sensitive to the ischaemic state in certain circumstances, whole blood measurements are equally applicable to the monitoring of trends in blood lactic acid.
本文描述了成人前臂在部分和完全动脉闭塞情况下，血浆和全血中乳酸血症的发展情况。在肱动脉完全闭塞的情况下，血浆隔室中的乳酸水平上升速度明显更快；梯度的平均差异为-11.6，95%置信区间为-15.6和-7.6。因此，在这些情况下，它们提供了一个更敏感的组织缺氧指标。在部分闭塞的情况下，没有显著差异；梯度的平均差异为1.0，95%置信区间为9.4和-7.3。虽然血浆乳酸水平在某些情况下对缺血状态更敏感，但全血测量同样适用于监测血乳酸的变化趋势。
