Pacios María Gabriela, Silva Clara, López María Elena, Cecilia Marta
Cátedra de Química Biológica, Facultad de Odontología, Universidad Nacional de Tucumán, San Miguel de Tucumán, Argentina.
J Investig Clin Dent. 2012 Nov;3(4):264-70. doi: 10.1111/j.2041-1626.2012.00147.x.
To evaluate the in vitro action of vehicles alone and with calcium hydroxide against different bacterial species.
Agar plates were inoculated with the microbial suspensions, and wells were made and filled with the calcium hydroxide pastes and the vehicles used to prepare the pastes. The zones of inhibited bacterial growth were recorded, and the resulting measurements were statistically analyzed.
Enterococcus faecalis was the most resistant microorganism to all medicaments. Calcium hydroxide + p-monochlorophenol; calcium hydroxide + p-monochlorophenol-propylene glycol pastes; and p-monochlorophenol, p-monochlorophenol-propylene glycol, and chlorhexidine gluconate gel alone showed the largest zones of inhibition against all the tested microorganisms.
The vehicle used to prepare the calcium hydroxide paste might contribute to its antibacterial action. Chlorhexidine gluconate gel used alone, and camphorated p-monochlorophenol and camphorated p-monochlorophenol-propylene glycol as vehicles of calcium hydroxide, could be recommended, in an antimicrobial sense.
评估单独使用赋形剂以及赋形剂与氢氧化钙联合对不同细菌种类的体外作用。
将微生物悬液接种于琼脂平板上，打孔并填充氢氧化钙糊剂及用于制备糊剂的赋形剂。记录细菌生长抑制区，并对所得测量结果进行统计学分析。
粪肠球菌对所有药物的耐受性最强。单独的氢氧化钙+对氯苯酚；氢氧化钙+对氯苯酚-丙二醇糊剂；以及单独的对氯苯酚、对氯苯酚-丙二醇和葡萄糖酸氯己定凝胶对所有测试微生物显示出最大的抑制区。
用于制备氢氧化钙糊剂的赋形剂可能有助于其抗菌作用。从抗菌意义上讲，可推荐单独使用葡萄糖酸氯己定凝胶，以及使用樟脑对氯苯酚和樟脑对氯苯酚-丙二醇作为氢氧化钙的赋形剂。
