韩国 15 家三级医院血源分离株念珠菌对两性霉素 B、氟康唑、伏立康唑和氟胞嘧啶的药敏性
Antifungal susceptibility to amphotericin B, fluconazole, voriconazole, and flucytosine in Candida bloodstream isolates from 15 tertiary hospitals in Korea.
机构信息
Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
出版信息
Ann Lab Med. 2012 Nov;32(6):426-8. doi: 10.3343/alm.2012.32.6.426. Epub 2012 Oct 17.
Abstract
The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4 antifungal drugs remain low among Candida bloodstream isolates in Korea.
摘要
采用 Vitek-2 酵母药敏系统（法国生物梅里埃公司），对来自韩国 15 家三级医院的 636 株念珠菌血流感染分离株进行了体外抗真菌药敏试验。结果显示，两性霉素 B、氟康唑、伏立康唑和氟胞嘧啶的总体药敏率分别为 98.1%、95.9%、99.1%和 97.3%。这表明韩国念珠菌血流感染分离株对 4 种抗真菌药物的耐药率仍然较低。
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