Grandesso Stefano, Sapino Barbara, Mazzuccato Sandra, Solinas Maria, Bedin Maria, D'Angelo Monica, Gion Massimo
Struttura Semplice Dipartimentale di Microbiologia, Ospedale dell'Angelo, Mestre, Venezia, Italy.
Infez Med. 2012 Mar;20(1):25-30.
In recent years the incidence of bloodstream infections due to Candida species has progressively increased, partly due to the more critical conditions of hospitalized patients. There has been a significant increase in immune-compromised, diabetic and/or elderly patients, also with venous access, with a subsequent increase in Candida species isolated from bloodstream infections. In 2009-2010 in the hospitals of Mestre and Venice we isolated 123 Candida species from bloodstream infections: 59 Candida albicans, 28 Candida parapsilosis, 12 Candida glabrata, 9 Candida tropicalis, and 4 Geotrichum capitatum, while the 11 others belong to 8 different species. We calculated MIC for the following antifungal agents: fluconazole, itraconazole, voriconazole, 5-flucytosine, amphotericin B and caspofungin.
近年来,念珠菌属引起的血流感染发病率逐渐上升,部分原因是住院患者病情更为危重。免疫功能低下、糖尿病和/或老年患者数量显著增加,且这些患者也有静脉通路,随后从血流感染中分离出的念珠菌属也有所增加。2009 - 2010年,我们在梅斯特雷和威尼斯的医院从血流感染中分离出123株念珠菌属:59株白色念珠菌、28株近平滑念珠菌、12株光滑念珠菌、9株热带念珠菌和4株头状地霉,而其他11株属于8个不同的种。我们计算了以下抗真菌药物的最低抑菌浓度:氟康唑、伊曲康唑、伏立康唑、5-氟胞嘧啶、两性霉素B和卡泊芬净。