Romano Mario R, Zenoni Stefano, Arpa Paolo, Mariotti Cesare
Istituto Clinico Humanitas, Rozzano, Milan, Italy.
Eur J Ophthalmol. 2013 Mar-Apr;23(2):230-5. doi: 10.5301/ejo.5000215.
To report the efficacy and ocular tolerance of a new tamponade made with ether and silicone oil (HeavySil [HSIL]) for the treatment of retinal detachment (RD) complicated by inferior proliferative vitreous retinopathy (PVR).
Prospective noncomparative interventional study on 31 consecutive eyes that underwent pars plana vitrectomy and were treated with HSIL as an intraocular tamponade. All patients presented with at least one retinal break and grade B-C PVR located between 4 and 8 o'clock. The main endpoint criteria were retinal reattachment after the removal of HSIL and complications arisen from the use of this tamponade.
Primary anatomic success was achieved in 27 out of 31 cases. Mean visual acuity improved from logMAR 1.4 (SD 0.7) to logMAR 1.1 (SD 0.6) (p=0.02). The main complications reported were cataract formation (5 out of 7 phakic eyes cases), clinically visible emulsification (6 cases), and difficulty of oil removal in 3 cases. Severe intraocular inflammation with HSIL in situ was found in only one case.
HeavySil, a saturated solution of ether with silicone oil, is a safe and effective tamponade agent for the treatment of complicated RD. The most common complications are cataract formation and oil emulsification.
报告一种由乙醚和硅油制成的新型填塞物（重硅油[HSIL]）用于治疗并发下方增殖性玻璃体视网膜病变（PVR）的视网膜脱离（RD）的疗效和眼耐受性。
对31只连续接受玻璃体切除术并使用HSIL作为眼内填塞物治疗的眼睛进行前瞻性非对照干预研究。所有患者均至少有一个视网膜裂孔，且B - C级PVR位于4点至8点之间。主要终点标准为HSIL取出后的视网膜复位情况以及使用该填塞物引起的并发症。
31例中有27例获得原发性解剖学成功。平均视力从logMAR 1.4（标准差0.7）提高到logMAR 1.1（标准差0.6）（p = 0.02）。报告的主要并发症为白内障形成（7例有晶状体眼中的5例）、临床可见的乳化（6例）和3例硅油取出困难。仅1例发现原位HSIL引起的严重眼内炎症。
重硅油，一种乙醚与硅油的饱和溶液，是治疗复杂性RD的一种安全有效的填塞剂。最常见的并发症是白内障形成和油乳化。
