Community Medicine Department, School of Medicine, Isfahan University of Medical Sciences, Hezar Jerib St., Isfahan, Iran.
Support Care Cancer. 2013 May;21(5):1219-25. doi: 10.1007/s00520-012-1650-1. Epub 2012 Nov 10.
Psychological distress and morbidity are common consequences of diagnosis and treatment of breast cancer and associated with poor quality of life (QOL). Spiritual well-being is an important aspect of QOL, but little is known about the spiritual well-being and its relationship with QOL in patients of different cultures such as Iranian Muslim patients. The aim of this study was to investigate the association of QOL and spirituality among patients with breast cancer undergoing radiation therapy.
This was a cross-sectional study which was conducted in the Breast Cancer Research Center of St. S. Al-Shohada Hospital, Isfahan, Iran. Spiritual well-being was measured using the Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale (FACIT-Sp12). The European Organisation for Research and Treatment of Cancer Quality of Life (EORTC QLQ-C30) and its supplementary breast cancer questionnaire (QLQ-BR23) were used to assess the quality of life of patients. Descriptive analysis, Pearson's correlation, and multiple regression analysis were performed for statistical assessment.
In all, 68 patients fulfilled the study's inclusion criteria and were interviewed. The mean global QOL was 41.42 (SD = 18.02), and the mean spiritual well-being was 28.41 (SD = 6.95). There was a significant positive correlation between general QOL and total spiritual well-being scores. Also, spiritual well-being, social functioning, pain, and arm symptoms were significant predictors of global QOL.
The results of this study provide evidence that breast cancer survivors in Iran experience a poor quality of life across a broad spectrum of health domains, particularly social, emotional, and spiritual, indicating that psychosocial-spiritual support should be considered in caring for patients with breast cancer.
心理困扰和发病是乳腺癌诊断和治疗的常见后果，与生活质量（QOL）差有关。精神幸福感是 QOL 的一个重要方面，但对于不同文化背景的患者，如伊朗穆斯林患者，其精神幸福感及其与 QOL 的关系知之甚少。本研究旨在探讨接受放射治疗的乳腺癌患者的 QOL 与精神幸福感之间的关联。
这是一项横断面研究，在伊朗伊斯法罕圣沙乌达医院的乳腺癌研究中心进行。采用慢性病患者的功能评估-精神幸福感量表（FACIT-Sp12）来衡量精神幸福感。欧洲癌症研究与治疗组织生活质量问卷（EORTC QLQ-C30）及其补充乳腺癌问卷（QLQ-BR23）用于评估患者的生活质量。进行描述性分析、皮尔逊相关分析和多元回归分析进行统计评估。
共有 68 名患者符合研究纳入标准并接受了访谈。总体 QOL 的平均得分为 41.42（SD=18.02），精神幸福感的平均得分为 28.41（SD=6.95）。一般 QOL 与总精神幸福感得分之间存在显著正相关。此外，精神幸福感、社会功能、疼痛和手臂症状是全球 QOL 的显著预测因素。
本研究结果提供了证据表明，伊朗的乳腺癌幸存者在广泛的健康领域（特别是社会、情感和精神领域）经历了较差的生活质量，这表明在照顾乳腺癌患者时应考虑心理社会-精神支持。
