Muhammad Jibran Sualeh, Zaidi Syed Faisal, Sugiyama Toshiro
Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan.
J Pak Med Assoc. 2012 Sep;62(9):955-9.
Helicobacter pylori infection is now recognised as a worldwide problem. It is the most common cause of chronic gastritis, and is strongly linked to peptic ulcer disease and gastric cancer. A comprehensive understanding of epidemiological ins and outs of H. pylori infection is very important in solving the patho-physiological enigma and might help in leading towards better management and prognosis of infection. This article presents a review of the literature on the epidemiology of H. pylori infection from 2006 to 2011. The authors used Medical Subject Heading (MeSH) terms 'Helicobacter' with 'epidemiology,' 'transmission' or 'risk factor' to search PubMed database. All relevant studies identified were included. Despite extensive medical advancement, many questions on Helicobacter pylori epidemiology still remain unanswered. Further studies are, therefore, required to gain a better understanding of the transmission pathway of this notorious pathogen.
幽门螺杆菌感染如今被公认为一个全球性问题。它是慢性胃炎最常见的病因，与消化性溃疡病和胃癌密切相关。全面了解幽门螺杆菌感染的流行病学细节对于解开病理生理谜团非常重要，并且可能有助于更好地管理感染及改善预后。本文对2006年至2011年期间幽门螺杆菌感染的流行病学文献进行了综述。作者使用医学主题词（MeSH）“幽门螺杆菌”与“流行病学”、“传播”或“危险因素”来检索PubMed数据库。纳入所有识别出的相关研究。尽管医学取得了长足进步，但关于幽门螺杆菌流行病学的许多问题仍然没有答案。因此，需要进一步开展研究以更好地了解这种臭名昭著的病原体的传播途径。
