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评价台湾植物区系 5 种土沉香属植物叶的体外抗氧化活性。

Evaluation of the antioxidant activity of five endemic Ligustrum species leaves from Taiwan flora in vitro.

机构信息

Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, No.91, Hsueh Shih Road, Taichung, 40402, Taiwan, ROC.

出版信息

Food Chem. 2011 Jul 15;127(2):564-71. doi: 10.1016/j.foodchem.2011.01.041. Epub 2011 Jan 18.

DOI:10.1016/j.foodchem.2011.01.041
PMID:23140701
Abstract

Leaves from the plant species belonging to the genus Ligustrum are widely used as tea or herbal medicine in Europe, China, and Japan. The antioxidant properties of five Ligustrum species from Taiwan were compared using in vitro antioxidant methods such as DPPH radical scavenging, TEAC, and FRAP assays. Cell-based antioxidant methods were used, including Fe(2+)/ascorbate-induced lipid peroxidation on brain homogenate and AAPH-induced erythrocyte haemolysis. The amounts of major phenolic compounds from the Ligustrum species, including phenylpropanoids, flavonoids, and iridoids, were determined by spectrophotometric methods. The results showed that all Ligustrum species exhibited antioxidant, radical-scavenging, anti-haemolytic, and lipid peroxidation-inhibiting activities at different magnitudes of potency. A significant correlation was found between antioxidant activity and the amount of antioxidant components, in particular, total phenolics and phenylpropanoids. Among all Ligustrum species from Taiwan, Ligustrum morrisonense is presented as potential source of natural antioxidants.

摘要

从木樨科女贞属植物的叶子被广泛用作茶或中草药在欧洲,中国和日本。五种台湾女贞属植物的抗氧化性能进行了比较,采用体外抗氧化方法,如 DPPH 自由基清除、TEAC 和 FRAP 测定。采用细胞抗氧化方法,包括脑匀浆中铁(2+)/抗坏血酸诱导的脂质过氧化和 AAPH 诱导的红细胞溶血。通过分光光度法测定女贞属植物中主要酚类化合物的含量,包括苯丙素、类黄酮和环烯醚萜。结果表明,所有女贞属植物均表现出不同程度的抗氧化、自由基清除、抗溶血和抑制脂质过氧化活性。抗氧化活性与抗氧化成分,特别是总酚类和苯丙素的含量之间存在显著相关性。在台湾所有的女贞属植物中,女贞子被认为是天然抗氧化剂的潜在来源。

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