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性别发育障碍重建手术的时机和性质 - 引言。

Timing and nature of reconstructive surgery for disorders of sex development - introduction.

机构信息

University College London Hospitals, UK.

出版信息

J Pediatr Urol. 2012 Dec;8(6):602-10. doi: 10.1016/j.jpurol.2012.10.001. Epub 2012 Nov 9.

Abstract

The ideal timing and nature of surgical reconstruction in individuals with Disorders of Sex Development (DSD) is highly controversial. Despite the increasing number of publications on this topic, evidence-based recommendations still cannot be made. However it is generally accepted that optimal care for DSD requires an experienced multidisciplinary team. This means that surgical decisions are now made within the context of a multidisciplinary team and all members of the team - and not just specialist surgeons - may be called upon to discuss choices for surgery with patients and parents. To do this well, every clinician in the team should have an understanding of the range of techniques available for genital surgery, the risks and benefits of procedures and the controversies surrounding timing of surgery. The aim of this paper is to give an overview of the variety of surgical procedures in current use and in what situation a particular technique would be indicated. The short-term risks and benefits are described and where available long-term outcome data is discussed. To date, discussions surrounding genital surgery have been led primarily by surgeons. Some non-surgical clinicians have expressed unease about decision making in genital surgery but have felt ill equipped to comment on an area with which they are unfamiliar. This review gives a detailed explanation of current surgical practice offered in a specialized center for DSD and such information should facilitate a more balanced discussion.

摘要

在性别发育障碍(DSD)患者中,手术重建的理想时机和性质存在很大争议。尽管关于这个主题的出版物越来越多,但仍然无法提出基于证据的建议。然而,人们普遍认为,DSD 的最佳治疗需要有经验的多学科团队。这意味着手术决策现在是在多学科团队的背景下做出的,团队的所有成员——而不仅仅是专科医生——可能都需要与患者和家长讨论手术选择。为了做好这一点,团队中的每位临床医生都应该了解可用于生殖器手术的各种技术、手术的风险和益处,以及手术时机方面的争议。本文的目的是概述目前使用的各种手术程序,以及在什么情况下会采用特定的技术。本文描述了短期风险和益处,以及在可用的情况下讨论了长期结果数据。迄今为止,生殖器手术的讨论主要由外科医生主导。一些非外科临床医生对生殖器手术的决策感到不安,但他们觉得自己没有能力对他们不熟悉的领域发表意见。本综述详细解释了在 DSD 专科中心提供的当前手术实践,此类信息应有助于进行更平衡的讨论。

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