Hedelin H, Grenabo L, Petterson S
Department of Urology, Sahlgrenska Hospital, University of Göteborg, Sweden.
Urol Res. 1990;18(1):35-8. doi: 10.1007/BF00294579.
Previous studies have shown human urine to have an inhibitory action on urease-induced crystallisation. Centrifugation and 0.45 microns filtration of the urine did not reduce this activity. This eliminates larger urine particles as being the cause of the inhibitory activity. Both the retenate and the filtrate after ultrafiltration of urine with a 100.000 mol weight cut-off influenced the urease-induced crystallisation of magnesium ammonium phosphate and calcium phosphate. The results indicate that the inhibitory action is exerted by more than one urinary component.
先前的研究表明，人类尿液对脲酶诱导的结晶具有抑制作用。尿液经离心和0.45微米过滤后，这种活性并未降低。这排除了较大的尿液颗粒是抑制活性的原因。用截留分子量为100,000的超滤膜对尿液进行超滤后，截留物和滤液均影响了脲酶诱导的磷酸镁铵和磷酸钙结晶。结果表明，这种抑制作用是由多种尿液成分共同发挥的。
