Kantor A F, Curnen M G, Meigs J W, Flannery J T
J Epidemiol Community Health. 1979 Dec;33(4):253-6. doi: 10.1136/jech.33.4.253.
A case-control study of 149 Connecticut-born children with Wilms's tumour reported to the Connecticut Tumor Registry during the period 1935--1973 and of 149 matched controls was undertaken in order to explore the possibility that children with Wilms's tumour may have been exposed perinatally to carcinogenic agents. The occupation of the father at the time of the child's birth was investigated and used as an indicator of potential sources of carcinogens to which infants in the study may have been exposed. An association was found between paternal occupations related to lead in the group developing Wilms's tumour compared with the controls.
一项病例对照研究对1935年至1973年间向康涅狄格肿瘤登记处报告的149名出生于康涅狄格州的患肾母细胞瘤儿童以及149名匹配对照儿童展开，旨在探究患肾母细胞瘤的儿童在围产期可能接触致癌物质的可能性。研究调查了孩子出生时父亲的职业，并将其作为研究中婴儿可能接触的潜在致癌物来源的指标。结果发现，与对照组相比，患肾母细胞瘤组中与铅相关的父亲职业之间存在关联。
