Fabia J, Thuy T D
Br J Prev Soc Med. 1974 May;28(2):98-100. doi: 10.1136/jech.28.2.98.
Occupation of father at time of birth was ascertained for a series of 386 children who died of malignant disease before age 5 during the years 1965-70 in the province of Quebec and a control group of 772 children whose birth registration immediately preceded and followed that of each case in the official files. The comparison of cases with controls showed a significant excess of fathers in hydrocarbon-related occupations among the cases with relative odds of 2·1. These occupations included, in particular, motor-vehicle mechanics, machinists, miners, and painters. On the other hand, cases and controls did not differ with regard to place of residence of parents or mean paternal age. The possible role of father's occupation in the risk of malignant disease of his offspring seems to deserve further investigation.
我们确定了1965年至1970年间在魁北克省5岁前死于恶性疾病的386名儿童以及一个对照组中儿童出生时其父亲的职业。对照组由772名儿童组成,他们的出生登记在官方档案中紧接在每个病例之前和之后。病例组与对照组的比较显示,病例组中从事与碳氢化合物相关职业的父亲显著多于对照组,相对比值为2.1。这些职业尤其包括机动车机械师、机械师、矿工和油漆工。另一方面,病例组和对照组在父母居住地或父亲平均年龄方面没有差异。父亲的职业在其后代患恶性疾病风险中可能起到的作用似乎值得进一步研究。