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肺腺癌患者皮肤癌性淋巴管炎:病例报告及文献复习。

Cutaneous lymphangitis carcinomatosa in a patient with lung adenocarcinoma: case report and literature review.

机构信息

AP-HP, Hôpital Saint-Antoine, Service de Médecine Interne, Paris 75012, France.

出版信息

Lung Cancer. 2013 Jan;79(1):91-3. doi: 10.1016/j.lungcan.2012.09.009. Epub 2012 Nov 17.

Abstract

We report the case of a man with a seven year history of lung adenocarcinoma who was diagnosed with cutaneous lymphangitis carcinomatosa. Skin examination revealed both an asymptomatic erysepelatoid rash localized on the posterior chest and an erythematous, eczematiform, itchy rash on the right anterior chest and on the left shoulder. Histopathologic examination of biopsies of these lesions revealed the same aspect with an infiltration of the dermal lymphatics by metastatic adenocarcinomatous cells. Cutaneous lymphangitis carcinomatosa is a rare condition accounting for less than 5% of skin metastases. A literature review identified eight other cases of cutaneous lymphangitis carcinomatosa in patients with lung cancer.

摘要

我们报告了一例患有肺腺癌七年病史的男性患者,该患者被诊断为皮肤淋巴管癌病。皮肤检查显示,患者的后胸部有一处无症状的红斑疹样皮疹,右前胸和左肩有红斑、湿疹样、瘙痒性皮疹。这些病变的活检组织病理学检查显示相同的特征,即真皮淋巴管被转移性腺癌细胞浸润。皮肤淋巴管癌病是一种罕见的疾病,占皮肤转移的不到 5%。文献回顾确定了另外 8 例患有肺癌的皮肤淋巴管癌病患者。

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