• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

老年成人偶然发现肺淋巴管癌病:1例极其罕见的病例报告。

Incidental detection of pulmonary lymphangitis carcinomatosis in an old adult: An exceedingly rare case report.

作者信息

Abdul-Hafez Hamza A, Zayed Alaa, Maraqa Mohammed A, Natsheh Motaz, Asbeh Yousef Abu

机构信息

Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.

Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.

出版信息

Int J Surg Case Rep. 2025 Feb;127:110836. doi: 10.1016/j.ijscr.2025.110836. Epub 2025 Jan 3.

DOI:10.1016/j.ijscr.2025.110836
PMID:39778498
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11760287/
Abstract

INTRODUCTION AND IMPORTANCE

Pulmonary lymphangitis carcinomatosis (PLC) is a rare and aggressive condition that silently spreads cancer cells through the lungs' lymphatic system. Often linked to advanced malignancies, PLC often mimics other pulmonary diseases, making diagnosis challenging. This report shares the unique case of an asymptomatic patient whose routine follow-up imaging led to the early discovery of PLC, highlighting the life-saving potential of attentive medical care.

CASE PRESENTATION

A 58-year-old man, previously treated for a benign colonic growth, found to have a small nodule on routine imaging. Though he had no symptoms, the nodule grew over six months, prompting surgery. Histopathological examination revealed early PLC secondary to an undiagnosed lung adenocarcinoma. Timely diagnosis and treatment, including surgery and chemotherapy, led to a favorable initial outcome.

DISCUSSION

This case highlights the importance of careful follow-up care and early detection, especially in asymptomatic individuals. PLC is rarely diagnosed in the absence of symptoms, and its incidental discovery provides a valuable opportunity for timely intervention. This report emphasizes the need for heightened awareness among clinicians to improve outcomes in such rare and challenging cases.

CONCLUSION

The case underscores the value of vigilant follow-up and thorough imaging evaluations, even in asymptomatic patients. Early detection of PLC can significantly alter the course of treatment and prognosis, reinforcing the importance of proactive medical care.

摘要

引言与重要性

肺淋巴管癌病(PLC)是一种罕见且侵袭性强的疾病,癌细胞通过肺部淋巴系统悄然扩散。PLC常与晚期恶性肿瘤相关,常与其他肺部疾病相似,诊断具有挑战性。本报告分享了一例无症状患者的独特病例,其常规随访影像学检查导致PLC的早期发现,突出了细心医疗护理的救命潜力。

病例介绍

一名58岁男性,曾接受过良性结肠肿物治疗,在常规影像学检查中发现一个小结节。尽管他没有症状,但结节在六个月内增大,促使进行手术。组织病理学检查显示为未诊断出的肺腺癌继发早期PLC。及时的诊断和治疗,包括手术和化疗,带来了良好的初始结果。

讨论

该病例突出了仔细的随访护理和早期检测的重要性,尤其是在无症状个体中。PLC在没有症状的情况下很少被诊断出来,其偶然发现为及时干预提供了宝贵机会。本报告强调临床医生需要提高认识,以改善此类罕见且具有挑战性病例的治疗结果。

结论

该病例强调了即使在无症状患者中进行警惕的随访和全面影像学评估的价值。PLC的早期发现可显著改变治疗进程和预后,强化了积极医疗护理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d2/11760287/afd90044d8dd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d2/11760287/ffa5ab104d0d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d2/11760287/afd90044d8dd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d2/11760287/ffa5ab104d0d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d2/11760287/afd90044d8dd/gr2.jpg

相似文献

1
Incidental detection of pulmonary lymphangitis carcinomatosis in an old adult: An exceedingly rare case report.老年成人偶然发现肺淋巴管癌病:1例极其罕见的病例报告。
Int J Surg Case Rep. 2025 Feb;127:110836. doi: 10.1016/j.ijscr.2025.110836. Epub 2025 Jan 3.
2
Pulmonary lymphangitis carcinomatosis: systematic review and meta-analysis of case reports, 1970-2018.肺淋巴管癌病:1970-2018 年病例报告的系统评价和荟萃分析。
Postgrad Med. 2019 Jun;131(5):309-318. doi: 10.1080/00325481.2019.1595982. Epub 2019 Apr 5.
3
[Clinical features and diagnosis of pulmonary lymphangitic carcinomatosis].[肺淋巴管癌病的临床特征与诊断]
Ai Zheng. 2006 Sep;25(9):1127-30.
4
Pulmonary lymphangitic carcinomatosis without concurrent liver metastasis from colon cancer detected using 18F-FDG PET/CT: A case report.18F-FDG PET/CT检测到的无结肠癌并发肝转移的肺淋巴管癌病:一例报告
Medicine (Baltimore). 2019 Oct;98(41):e17446. doi: 10.1097/MD.0000000000017446.
5
Pulmonary lymphangitis carcinomatosis: A peculiar presentation clustering in MET-amplified gastric cancer.肺淋巴管癌病:一种在MET扩增的胃癌中聚集出现的特殊表现。
Cancer Med. 2023 Oct;12(19):19583-19594. doi: 10.1002/cam4.6575. Epub 2023 Sep 29.
6
A Case of Rapidly Deteriorating Lymphangitic Carcinomatosis in a Patient with Stage IV Pancreatic Cancer.一例IV期胰腺癌患者迅速恶化的淋巴管癌病病例
Cureus. 2019 Apr 9;11(4):e4421. doi: 10.7759/cureus.4421.
7
Folliculotropic Cutaneous Metastases and Lymphangitis Carcinomatosa: When Cutaneous Metastases of Breast Carcinoma Are Mistaken for Cutaneous Infections.毛囊性皮肤转移瘤和癌性淋巴管炎:乳腺癌皮肤转移被误诊为皮肤感染时的情况。
Acta Dermatovenerol Croat. 2016 Jun;24(2):154-7.
8
Respiratory failure due to pulmonary lymphangitis carcinomatosis.肺淋巴管癌病所致呼吸衰竭
Chest. 1993 Mar;103(3):967-8. doi: 10.1378/chest.103.3.967.
9
Incidental detection of an appendiceal neuroendocrine tumor in a right hemicolectomy specimen for colonic adenocarcinoma: A case report.在因结肠腺癌行右半结肠切除术的标本中偶然发现阑尾神经内分泌肿瘤:一例报告。
Int J Surg Case Rep. 2024 Sep;122:110121. doi: 10.1016/j.ijscr.2024.110121. Epub 2024 Aug 3.
10
Clinical outcome of pulmonary lymphangitic carcinomatosis in gynecologic malignancy: A single-institution experience.妇科恶性肿瘤肺淋巴管癌病的临床结局:单中心经验。
Taiwan J Obstet Gynecol. 2022 Mar;61(2):333-338. doi: 10.1016/j.tjog.2022.02.024.

本文引用的文献

1
The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2023 指南:更新共识外科病例报告(SCARE)指南。
Int J Surg. 2023 May 1;109(5):1136-1140. doi: 10.1097/JS9.0000000000000373.
2
Prognostic value of pretherapeutic FDG PET/CT in non-small cell lung cancer with pulmonary lymphangitic carcinomatosis.术前 FDG PET/CT 对肺淋巴管癌病非小细胞肺癌的预后价值。
Sci Rep. 2023 Jan 7;13(1):345. doi: 10.1038/s41598-022-24875-2.
3
Evaluating the Patient With a Pulmonary Nodule: A Review.评估肺部结节患者:综述。
JAMA. 2022 Jan 18;327(3):264-273. doi: 10.1001/jama.2021.24287.
4
Pulmonary Lymphangitic Carcinomatosis: Diagnostic Performance of High-Resolution CT and F-FDG PET/CT in Correlation with Clinical Pathologic Outcome.肺淋巴管癌病:高分辨率 CT 与 F-FDG PET/CT 对临床病理结局的诊断性能。
J Nucl Med. 2020 Jan;61(1):26-32. doi: 10.2967/jnumed.119.229575. Epub 2019 Jun 21.
5
Pulmonary lymphangitis carcinomatosis: systematic review and meta-analysis of case reports, 1970-2018.肺淋巴管癌病:1970-2018 年病例报告的系统评价和荟萃分析。
Postgrad Med. 2019 Jun;131(5):309-318. doi: 10.1080/00325481.2019.1595982. Epub 2019 Apr 5.
6
A Rare Case of Isolated Chronic Cough Caused by Pulmonary Lymphangitic Carcinomatosis as a Primary Manifestation of Rectum Carcinoma.以肺淋巴管癌病为首发表现的直肠癌致孤立性慢性咳嗽1例罕见病例
Intern Med. 2018 Sep 15;57(18):2709-2712. doi: 10.2169/internalmedicine.0572-17. Epub 2018 May 18.
7
Clinical and organizational factors in the initial evaluation of patients with lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.肺癌患者初始评估的临床和组织学因素:肺癌的诊断和治疗,第 3 版:美国胸科医师学会循证临床实践指南。
Chest. 2013 May;143(5 Suppl):e121S-e141S. doi: 10.1378/chest.12-2352.
8
Prognostic significance of vascular and lymphatic emboli in resected pulmonary adenocarcinoma.切除的肺腺癌中血管和淋巴管内瘤栓的预后意义。
Ann Thorac Surg. 2013 Apr;95(4):1204-10. doi: 10.1016/j.athoracsur.2012.12.024. Epub 2013 Feb 14.
9
Cutaneous lymphangitis carcinomatosa in a patient with lung adenocarcinoma: case report and literature review.肺腺癌患者皮肤癌性淋巴管炎:病例报告及文献复习。
Lung Cancer. 2013 Jan;79(1):91-3. doi: 10.1016/j.lungcan.2012.09.009. Epub 2012 Nov 17.
10
[Clinical investigation of application of lung biopsy in the diagnosis of diffuse pulmonary interstitial disease].肺活检在弥漫性肺间质疾病诊断中应用的临床研究
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2004 Oct;16(10):615-7.